The development of cancer is due to the accumulation of multiple somatic mutations and in
some cases due to germline mutations, which occur in malignancies such as retinoblastoma …

This review considers the biology of the type 1 growth factor receptor family which is
increasingly recognised as important in the control of normal cell proliferation and in the …

The vLAMPS is a human, biomimetic liver MPS, in which the ECM and cell seeding of the
intermediate layer prior to assembly, simplifies construction of the model and makes the …

Introduction 3. The EGF-related growth factors 4. The EGF-CFC family 5. The erbB receptor
family 6. EGF-like growth factors in cell proliferation and oncogenesis 6.1 The EGF-like …

Chronic airway inflammation, one of the pathophysiologic features of bronchial asthma, is
suspected to be responsible for irreversible pathological changes of airways, called airway …

In this review article, we will first provide a brief overview of the ErbB receptor–ligand system
and its importance in developmental and physiological processes. We will then review the …

The ERBB or EGF receptor (EGFR) proto-oncogene family, which consists of four structurally-
related transmembrane receptors (ie, EGFR, ErbB2, ErbB3, and ErbB4), plays an etiological …

The results of recent studies suggest that overexpression of the EGF receptor accompanied
by production of its ligands is an important characteristic of human squamous cell …

Objective To evaluate the role of urinary epidermal growth factor (EGF) as a biomarker of
chronic kidney damage in lupus nephritis (LN). Methods A proteomics approach was used to …

A number of growth factors have been implicated as stimuli of thyroid cell proliferation;
overexpression of these growth factors and/or their receptors may play a role in the growth of …