Biosynthesis and metabolic engineering of isoflavonoids in model plants and crops: A review

L Wang, C Li, K Luo - Frontiers in Plant Science, 2024 - frontiersin.org
Isoflavonoids, the major secondary metabolites within the flavonoid biosynthetic pathway,
play important roles in plant defense and exhibit free radical scavenging properties in …

High-quality genome of a modern soybean cultivar and resequencing of 547 accessions provide insights into the role of structural variation

C Zhang, Z Shao, Y Kong, H Du, W Li, Z Yang, X Li… - Nature Genetics, 2024 - nature.com
Soybean provides protein, oil and multiple health-related compounds. Understanding the
effects of structural variations (SVs) on economic traits in modern breeding is important for …

Plant–environment response pathway regulation uncovered by investigating non-typical legume symbiosis and nodulation

H Wilkinson, A Coppock, BL Richmond, B Lagunas… - Plants, 2023 - mdpi.com
Nitrogen is an essential element needed for plants to survive, and legumes are well known
to recruit rhizobia to fix atmospheric nitrogen. In this widely studied symbiosis, legumes …

Metabolomics and Transcription Profiling of Pumpkin Fruit Reveals Enhanced Bioactive Flavonoids and Coumarins in Giant Pumpkin (Cucurbita maxima)

C Chen, L Xu, W Xia, C Qi, J Liu, B Hua… - Journal of Agricultural …, 2023 - ACS Publications
Atlantic giant (AG, Cucurbita maxima) is a type of giant pumpkin in the Cucurbitaceae family
and has the world's largest fruit. AG possesses excellent ornamental and economic value …

Integrated transcriptomic and metabolomic analysis reveals the molecular basis of tissue-specific accumulation of bioactive steroidal alkaloids in Fritillaria …

H Liao, H Quan, B Huang, H Ji, T Zhang, J Chen… - Phytochemistry, 2023 - Elsevier
Fritillaria unibracteata is an endangered medicinal plant whose bulb has been used as a
Chinese herb to suppress cough, asthma and excessive phlegm for centuries. Steroidal …

Identification of hub genes regulating isoflavone accumulation in soybean seeds via GWAS and WGCNA approaches

M Azam, S Zhang, J Li, M Ahsan… - Frontiers in Plant …, 2023 - frontiersin.org
Introduction Isoflavones are the secondary metabolites synthesized by the phenylpropanoid
biosynthesis pathway in soybean that benefits human and plant health. Methods In this …

Identification of genes for seed isoflavones based on bulk segregant analysis sequencing in soybean natural population

M Azam, S Zhang, Y Huai, AM Abdelghany… - Theoretical and Applied …, 2023 - Springer
Key message We identified four hub genes for isoflavone biosynthesis based on BSA-seq
and WGCNA methods and validated that GmIE3-1 positively contribute to isoflavone …

A C2H2‐type zinc finger protein ZAT12 of Poncirus trifoliata acts downstream of CBF1 to regulate cold tolerance

Y Zhang, W Xiao, M Wang, M Khan, JH Liu - The Plant Journal, 2024 - Wiley Online Library
SUMMARY The Cys2/His2 (C2H2)‐type zinc finger family has been reported to regulate
multiple aspects of plant development and abiotic stress response. However, the role of …

The GmSTF1/2–GmBBX4 negative feedback loop acts downstream of blue-light photoreceptors to regulate isoflavonoid biosynthesis in soybean

Z Song, F Zhao, L Chu, H Lin, Y Xiao, Z Fang… - Plant …, 2024 - cell.com
Isoflavonoids, secondary metabolites derived from the phenylalanine pathway, are
predominantly biosynthesized in legumes, especially soybean (Glycine max). They are not …

Joint GWAS and WGCNA Identify Genes Regulating the Isoflavone Content in Soybean Seeds

Z Yang, X Wu, Y Zhu, Y Qu, C Zhou… - Journal of Agricultural …, 2024 - ACS Publications
Isoflavone is a secondary metabolite of the soybean phenylpropyl biosynthesis pathway with
physiological activity and is beneficial to human health. In this study, the isoflavone content …