An aggressive interaction rapidly increases brain androgens in a male songbird during the non-breeding season

C Jalabert, SL Gray, KK Soma - Journal of Neuroscience, 2024 - Soc Neuroscience
Aggression is a crucial behavior that impacts access to limited resources in different
environmental contexts. Androgens synthesized by the gonads promote aggression during …

Isoflurane stress induces region-specific glucocorticoid levels in neonatal mouse brain

JE Hamden, KM Gray, M Salehzadeh… - Journal of …, 2022 - joe.bioscientifica.com
The profound programming effects of early life stress (ELS) on brain and behavior are
thought to be primarily mediated by adrenal glucocorticoids (GCs). However, in mice …

Profiling of adrenal corticosteroids in blood and local tissues of mice during chronic stress

K Vagnerová, M Jágr, C Mekadim, P Ergang… - Scientific Reports, 2023 - nature.com
Stress increases plasma concentrations of corticosteroids, however, their tissue levels are
unclear. Using a repeated social defeat paradigm, we examined the impact of chronic stress …

[HTML][HTML] Glucocorticoid production in the thymus and brain: Immunosteroids and neurosteroids

M Salehzadeh, KK Soma - Brain, Behavior, & Immunity-Health, 2021 - Elsevier
Glucocorticoids (GCs) regulate a myriad of physiological systems, such as the immune and
nervous systems. Systemic GC levels in blood are often measured as an indicator of local …

Pre-Test Manipulation by Intraperitoneal Saline Injection with or without Isoflurane Pre-Treatment Does Not Influence the Outcome of Social Test in Male Mice

F Pomogyi, B Török, D Zelena - Stresses, 2023 - mdpi.com
Preclinical studies on rodents should follow the 3R principle minimising the suffering of the
animals. To do so, some researchers use inhalation anaesthetic induction even before …

Prenatal glyphosate exposure disrupts the gut-brain axis across several generations in mice.

JA Barnett, JK Josephson, NA Haskey, MM Hart… - bioRxiv, 2024 - biorxiv.org
Glyphosate, a widely used herbicide in North America, has become prevalent in the food
supply due to preharvest applications, raising concerns about potential health impacts. This …

Inheriting the toxic effects of our ancestors diet: prenatal glyphosate exposure induces colonic inflammation, immune metabolic dysfunction and behavioral deficits in …

JA Barnett - 2024 - open.library.ubc.ca
Glyphosate, commonly known as Roundup®, is heavily used in Canada, with over 50 million
kilograms purchased annually. Its pre-harvest use results in residues in Canadian food …

Effects of lipopolysaccharide on local glucocorticoid regulation in the mouse nervous and immune systems

M Salehzadeh Moghadami - 2024 - open.library.ubc.ca
Immune activation during early development has long-term effects on health, increasing the
risk for neuropsychiatric disorders (eg, mood disorders, schizophrenia, autism) and immune …