Aging-related modifications to G protein-coupled receptor signaling diversity

J van Gastel, H Leysen, J Boddaert, LM Luttrell… - Pharmacology & …, 2021 - Elsevier
Aging is a highly complex molecular process, affecting nearly all tissue systems in humans
and is the highest risk factor in developing neurodegenerative disorders such as Alzheimer's …

Systemic inflammation, oxidative damage to nucleic acids, and metabolic syndrome in the pathogenesis of psoriasis

L Borska, J Kremlacek, C Andrys, J Krejsek… - International journal of …, 2017 - mdpi.com
In the pathogenesis of psoriasis, systemic inflammation and oxidative stress play mutual
roles interrelated with metabolic syndrome (MetS). This study aims to map the selected …

B1 siRNA Increases de novo DNA Methylation of B1 Elements and Promotes Wound Healing in Diabetic Rats

S Yasom, W Khumsri, P Boonsongserm… - Frontiers in Cell and …, 2022 - frontiersin.org
Alu (B1 in rodents) hypomethylation, commonly found in diabetes mellitus patients,
increases DNA damage and, consequently, delays the healing process. Alu siRNA …

The relationship between plasma lipids, oxidant–antioxidant status, and glycated proteins in individuals at risk for atherosclerosis

S Dzięgielewska-Gęsiak, A Płóciniczak… - … interventions in aging, 2019 - Taylor & Francis
Objective: Ageing is one of the major risks for atherosclerosis. The age-related changes of
interactions between plasma lipids, oxidative stress, antioxidant defense, and glycation …

Interaction of human IAPP and Aβ1-42 aggravated the AD-related pathology and impaired the cognition in mice

HC Chen, JX Cao, YT Cai, HL Du, XX Xi, J Sun… - Experimental …, 2020 - Elsevier
Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) have a common pathology.
Both diseases are characterized by local deposition of amyloid proteins in the brain or islet …

Effect of fluoride on the Expression of 8-Hydroxy-2′-deoxyguanosine in the blood, kidney, liver, and brain of rats

Y Ma, X Meng, A Sowanou, J Wang, H Li, A Li… - … Trace Element Research, 2023 - Springer
Excessive exposure of fluoride not only leads to damage on bone, but also has an adverse
effect on soft tissues. Oxidative DNA damage induced by fluoride is thought to be one of the …

The relationship between plasma lipids, oxidant--antioxidant status, and glycated proteins in individuals at risk for atherosclerosis.

S Dziegielewska-Gesiak, A Plociniczak… - … Interventions in Aging, 2019 - go.gale.com
The relationship between plasma lipids, oxidant--antioxidant status, and glycated proteins
in individuals at risk for atherosclerosis. - Document - Gale Academic OneFile Use this link …

Effect of adriamycin combined with metformin on biological function of human tongue cancer SSC-15 cells

J Zhang - Oncology Letters, 2019 - spandidos-publications.com
The effect of adriamycin (ADM) combined with metformin (MET) on the biological function of
human tongue cancer SSC-15 cells was investigated. SCC-15 cells (ATCC® CRL-1623) …

[PDF][PDF] A Cross-Sectional Study to Evaluate the Link between Oxidative Stress and Increased Cardiovascular Risks in Prediabetic Patients

FM Ahmed, AH Awla, SY Omar, BJ Hamadamin… - Kirkuk Journal of …, 2024 - iasj.net
Prediabetes is associated with dysglycemia; besides progression to diabetes mellitus,
prediabetic patients are at risk for cardiovascular disease (CVD). The current study is …

Effects of haem oxygenase-1 expression on oxidative injury and biological behaviours of rat dermal fibroblasts

Q Li, R Guo, K Zhao, D Lin, X Ye… - Journal of Wound …, 2018 - magonlinelibrary.com
Objective: This study investigated the effects of high haem oxygenase-1 (HO-1) expression
on oxidative injury and the biological behaviours of rat dermal fibroblasts, under high …