Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria
RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence
Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …
Cyclic di-GMP: the first 25 years of a universal bacterial second messenger
U Römling, MY Galperin… - … and Molecular Biology …, 2013 - Am Soc Microbiol
Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …
Escaping the biofilm in more than one way: desorption, detachment or dispersion
OE Petrova, K Sauer - Current opinion in microbiology, 2016 - Elsevier
Highlights•At least three types of “escapes” or ways for bacteria to leave the biofilm are
known.•Types of escapes are referred to as desorption, detachment, and …
known.•Types of escapes are referred to as desorption, detachment, and …
A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence
D Balasubramanian, L Schneper, H Kumari… - Nucleic acids …, 2013 - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …
How bacteria recognise and respond to surface contact
TEP Kimkes, M Heinemann - FEMS microbiology reviews, 2020 - academic.oup.com
Bacterial biofilms can cause medical problems and issues in technical systems. While a
large body of knowledge exists on the phenotypes of planktonic and of sessile cells in …
large body of knowledge exists on the phenotypes of planktonic and of sessile cells in …
Sticky situations: key components that control bacterial surface attachment
OE Petrova, K Sauer - Journal of bacteriology, 2012 - Am Soc Microbiol
The formation of bacterial biofilms is initiated by cells transitioning from the free-swimming
mode of growth to a surface. This review is aimed at highlighting the common themes that …
mode of growth to a surface. This review is aimed at highlighting the common themes that …
Pseudomonas aeruginosa biofilm infections: community structure, antimicrobial tolerance and immune response
M Rybtke, LD Hultqvist, M Givskov… - Journal of molecular …, 2015 - Elsevier
Studies of biopsies from infectious sites, explanted tissue and medical devises have
provided evidence that biofilms are the underlying cause of a variety of tissue-associated …
provided evidence that biofilms are the underlying cause of a variety of tissue-associated …
An update on Pseudomonas aeruginosa biofilm formation, tolerance, and dispersal
We review the recent advances in the understanding of the Pseudomonas aeruginosa
biofilm lifestyle from studies using in vitro laboratory setups such as flow chambers and …
biofilm lifestyle from studies using in vitro laboratory setups such as flow chambers and …