Transcription factors (TFs) participate in a wide range of cellular processes due to their
inherent function as essential regulatory proteins. Their dysfunction has been linked to …

Women live longer than men but experience greater disability and a longer period of illness
as they age. Despite clear sex differences in aging, the impact of pregnancy and its …

Recurrent pregnancy loss is a frequently occurring human infertility-related disease
affecting~ 1% of women. It has been estimated that the cause remains unexplained in> 50 …

The endometrium becomes receptive to the embryo only in the mid-luteal phase, but not in
the other stages of the menstrual cycle. Endometrial factors play an important role in …

Recurrent pregnancy loss (RPL) affects up to 5% of couples. It is believed that genetic
factors contribute to the disease's etiology and pathophysiology. Hundreds of genes …

Recent evidence entail paternal factors as plausible contributors in spontaneous recurrent
pregnancy loss (RPL). Seminal extracellular vesicles secreted from cells of male …

Background: Preeclampsia is a major hypertensive disease caused by pregnancy, inducing
proteinuria and increased blood pressure starting from the second half of pregnancy (early …

Deregulation of the Wnt/β-catenin pathway is associated with the development of human
cancer including colorectal and liver cancer. Although we previously showed that histidine …

Background Preeclampsia (PE) is a frequently occurring multisystemic disease affecting~
5% of pregnancies. PE patients may develop HELLP syndrome (haemolysis, elevated liver …

As a member of the forkhead box (FOX) family of transcription factors (TF), FOXD1 has
recently been implicated as a crucial regulator in a variety of human cancers. Accumulating …