Control of human viral infections by natural killer cells
S Jost, M Altfeld - Annual review of immunology, 2013 - annualreviews.org
Natural killer (NK) cells are effector cells of the innate immune system and are important in
the control of viral infections. Their relevance is reflected by the multiple mechanisms …
the control of viral infections. Their relevance is reflected by the multiple mechanisms …
Maternal KIR and fetal HLA-C: a fine balance
ABSTRACT NK cell effector function is regulated by a range of activating and inhibitory
receptors, and many of their known ligands are MHC class I molecules. Human NK …
receptors, and many of their known ligands are MHC class I molecules. Human NK …
Natural killer cell responses during viral infections: flexibility and conditioning of innate immunity by experience
Natural killer (NK) cells mediate innate defense against viral infections, but the mechanisms
in place to access their functions as needed during diverse challenges while limiting …
in place to access their functions as needed during diverse challenges while limiting …
KIR/HLA interactions and pathogen immunity
KM Jamil, SI Khakoo - BioMed Research International, 2011 - Wiley Online Library
The innate immune system is the first line of defence in response to pathogen infection.
Natural killer (NK) cells perform a vital role in this response with the ability to directly kill …
Natural killer (NK) cells perform a vital role in this response with the ability to directly kill …
NK cells: immune cross-talk and therapeutic implications
A Malhotra, A Shanker - Immunotherapy, 2011 - Taylor & Francis
Increased evidence of cross-talk between NK cells and other immune cells has enhanced
the possibilities of exploiting the interplay between the activation and inhibition of NK cells …
the possibilities of exploiting the interplay between the activation and inhibition of NK cells …
IL28B, HLA-C, and KIR Variants Additively Predict Response to Therapy in Chronic Hepatitis C Virus Infection in a European Cohort: A Cross-Sectional Study
V Suppiah, S Gaudieri, NJ Armstrong… - PLoS …, 2011 - journals.plos.org
Background To date, drug response genes have not proved as useful in clinical practice as
was anticipated at the start of the genomic era. An exception is in the treatment of chronic …
was anticipated at the start of the genomic era. An exception is in the treatment of chronic …
Natural killer cells and hepatitis C: action and reaction
K Cheent, SI Khakoo - Gut, 2011 - gut.bmj.com
In 1989, hepatitis C virus (HCV) was first identified as the infectious agent responsible for
human non-A, non-B hepatitis. Two decades later, HCV remains a global public health …
human non-A, non-B hepatitis. Two decades later, HCV remains a global public health …
[HTML][HTML] Genomics and HCV infection: progression of fibrosis and treatment response
E Estrabaud, M Vidaud, P Marcellin, T Asselah - Journal of hepatology, 2012 - Elsevier
HCV infection is a global health problem that affects 170 million people worldwide. The
severity of the disease varies from asymptomatic chronic infection to cirrhosis and …
severity of the disease varies from asymptomatic chronic infection to cirrhosis and …
Activating NK cell receptor expression/function (NKp30, NKp46, DNAM‐1) during chronic viraemic HCV infection is associated with the outcome of combined …
F Bozzano, A Picciotto, P Costa… - European journal of …, 2011 - Wiley Online Library
Specific NK cell killer inhibitory receptor (KIR): HLA haplotype combinations have been
associated with successful clearance of acute and chronic HCV infection. Whether an …
associated with successful clearance of acute and chronic HCV infection. Whether an …
IL‐12 and IL‐15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells
T Hydes, A Noll, G Salinas‐Riester… - Immunity …, 2018 - Wiley Online Library
Introduction Murine hepatic NK cells exhibit adaptive features, with liver‐specific adhesion
molecules CXCR6 and CD49a acting as surface markers. Methods We investigated human …
molecules CXCR6 and CD49a acting as surface markers. Methods We investigated human …