Status and prospects of genome‐wide association studies in plants

L Tibbs Cortes, Z Zhang, J Yu - The plant genome, 2021 - Wiley Online Library
Genome‐wide association studies (GWAS) have developed into a powerful and ubiquitous
tool for the investigation of complex traits. In large part, this was fueled by advances in …

[HTML][HTML] Genetic mapping of quantitative trait loci in crops

Y Xu, P Li, Z Yang, C Xu - The Crop Journal, 2017 - Elsevier
Dissecting the genetic architecture of complex traits is an ongoing challenge for geneticists.
Two complementary approaches for genetic mapping, linkage mapping and association …

A compressed variance component mixed model for detecting QTNs and QTN-by-environment and QTN-by-QTN interactions in genome-wide association studies

M Li, YW Zhang, ZC Zhang, Y Xiang, MH Liu, YH Zhou… - Molecular Plant, 2022 - cell.com
Although genome-wide association studies are widely used to mine genes for quantitative
traits, the effects to be estimated are confounded, and the methodologies for detecting …

Whole-genome resequencing reveals Brassica napus origin and genetic loci involved in its improvement

K Lu, L Wei, X Li, Y Wang, J Wu, M Liu, C Zhang… - Nature …, 2019 - nature.com
Abstract Brassica napus (2 n= 4 x= 38, AACC) is an important allopolyploid crop derived
from interspecific crosses between Brassica rapa (2 n= 2 x= 20, AA) and Brassica oleracea …

Comparing different statistical models and multiple testing corrections for association mapping in soybean and maize

AS Kaler, JD Gillman, T Beissinger… - Frontiers in plant …, 2020 - frontiersin.org
Association mapping (AM) is a powerful tool for fine mapping complex trait variation down to
nucleotide sequences by exploiting historical recombination events. A major problem in AM …

Methodological implementation of mixed linear models in multi-locus genome-wide association studies

YJ Wen, H Zhang, YL Ni, B Huang… - Briefings in …, 2018 - academic.oup.com
The mixed linear model has been widely used in genome-wide association studies (GWAS),
but its application to multi-locus GWAS analysis has not been explored and assessed. Here …

IIIVmrMLM: The R and C++ tools associated with 3VmrMLM, a comprehensive GWAS method for dissecting quantitative traits

M Li, YW Zhang, Y Xiang, MH Liu, YM Zhang - Molecular Plant, 2022 - cell.com
In most existing methods and softwares of genome-wide association studies (GWAS) for
detecting quantitative trait nucleotides (QTNs), QTN-by-environment interactions (QEIs), and …

mrMLM v4. 0.2: an R platform for multi-locus genome-wide association studies

YW Zhang, CL Tamba, YJ Wen, P Li… - Genomics …, 2020 - academic.oup.com
Previous studies have reported that some important loci are missed in single-locus genome-
wide association studies (GWAS), especially because of the large phenotypic error in field …

Iterative sure independence screening EM-Bayesian LASSO algorithm for multi-locus genome-wide association studies

CL Tamba, YL Ni, YM Zhang - PLoS computational biology, 2017 - journals.plos.org
Genome-wide association study (GWAS) entails examining a large number of single
nucleotide polymorphisms (SNPs) in a limited sample with hundreds of individuals, implying …

pLARmEB: integration of least angle regression with empirical Bayes for multilocus genome-wide association studies

J Zhang, JY Feng, YL Ni, YJ Wen, Y Niu, CL Tamba… - Heredity, 2017 - nature.com
Multilocus genome-wide association studies (GWAS) have become the state-of-the-art
procedure to identify quantitative trait nucleotides (QTNs) associated with complex traits …