Advanced neurobiological tools to interrogate metabolism

PN Mirabella, H Fenselau - Nature Reviews Endocrinology, 2023 - nature.com
Engineered neurobiological tools for the manipulation of cellular activity, such as
chemogenetics and optogenetics, have become a cornerstone of modern neuroscience …

Direct modulation of TRPC ion channels by Gα proteins

H Kang, J Kim, CH Park, B Jeong, I So - Frontiers in Physiology, 2024 - frontiersin.org
GPCR-Gi protein pathways are involved in the regulation of vagus muscarinic pathway
under physiological conditions and are closely associated with the regulation of internal …

A silicon diode–based optoelectronic interface for bidirectional neural modulation

X Fu, Z Hu, W Li, L Ma, J Chen, M Liu, J Liu… - Proceedings of the …, 2024 - pnas.org
The development of advanced neural modulation techniques is crucial to neuroscience
research and neuroengineering applications. Recently, optical-based, nongenetic …

Astrocyte-mediated regulation of BLAWFS1 neurons alleviates risk-assessment deficits in DISC1-N mice

X Zhou, Q Xiao, Y Liu, S Chen, X Xu, Z Zhang, Y Hong… - Neuron, 2024 - cell.com
Assessing and responding to threats is vital in everyday life. Unfortunately, many mental
illnesses involve impaired risk assessment, affecting patients, families, and society. The …

The hyperthermic response to intra-preoptic area administration of agmatine in male rats

J Xu, W Gao, T He, L Yao, H Wu, Z Chen, Y Lai… - Journal of Thermal …, 2023 - Elsevier
Agmatine is an endogenous biogenic amine that exerts various effects on the central
nervous system. The hypothalamic preoptic area (POA, thermoregulatory command center) …

Cerebral Lactate Participates in Hypoxia-induced Anapyrexia Through its Receptor G Protein-coupled Receptor 81

T Yang, Z Wang, J Li, F Shan, QY Huang - Neuroscience, 2024 - Elsevier
Hypoxia-induced anapyrexia is thought to be a regulated decrease in body core
temperature (T core), but the underlying mechanism remains unclear. Recent evidence …

Functional relationship between peripheral thermosensation and behavioral thermoregulation

T Suito, M Tominaga - Frontiers in Neural Circuits, 2024 - frontiersin.org
Thermoregulation is a fundamental mechanism for maintaining homeostasis in living
organisms because temperature affects essentially all biochemical and physiological …

Identification of the genetic characteristics of copy number variations in experimental specific pathogen-free ducks using whole-genome resequencing

L Li, J Quan, H Liu, H Yu, H Chen, C Xia, S Zhao… - BMC genomics, 2024 - Springer
Background Specific pathogen-free ducks are a valuable laboratory resource for waterfowl
disease research and poultry vaccine development. High throughput sequencing allows the …

Burning Question: How Does Our Brain Process Positive and Negative Cues Associated with Thermosensation?

JG Grajales-Reyes, B Chen, D Meseguer… - …, 2024 - journals.physiology.org
Whether it is the dramatic suffocating sensation from a heat wave in the summer or the
positive reinforcement arising from a hot drink on a cold day; we can certainly agree that our …

Hypothermia protects the integrity of corticospinal tracts and alleviates mitochondria injury after intracerebral hemorrhage in mice

E Sun, S Lu, C Yang, Z Li, Y Qian, Y Chen, S Chen… - Experimental …, 2024 - Elsevier
Disruption of corticospinal tracts (CST) is a leading factor for motor impairments following
intracerebral hemorrhage (ICH) in the striatum. Previous studies have shown that …