T cell immunity to bacterial pathogens: mechanisms of immune control and bacterial evasion

FR Shepherd, JE McLaren - International journal of molecular sciences, 2020 - mdpi.com
The human body frequently encounters harmful bacterial pathogens and employs immune
defense mechanisms designed to counteract such pathogenic assault. In the adaptive …

Laboratory water-window x-ray microscopy

M Kördel, A Dehlinger, C Seim, U Vogt, E Fogelqvist… - Optica, 2020 - opg.optica.org
Soft x-ray microscopy in the water window (∼ 285− 535 e V) is an emerging and unique tool
for 2D and 3D imaging of unstained intact cellular samples in their near-native state with few …

MISTRAL: a transmission soft X-ray microscopy beamline for cryo nano-tomography of biological samples and magnetic domains imaging

A Sorrentino, J Nicolás, R Valcárcel… - Journal of …, 2015 - journals.iucr.org
The performance of MISTRAL is reported, the soft X-ray transmission microscopy beamline
at the ALBA light source (Barcelona, Spain) which is primarily dedicated to cryo soft X-ray …

HLA-DR marks recently divided antigen-specific effector CD4 T cells in active tuberculosis patients

R Tippalagama, A Singhania, P Dubelko… - The Journal of …, 2021 - journals.aai.org
Upon Ag encounter, T cells can rapidly divide and form an effector population, which plays
an important role in fighting acute infections. In humans, little is known about the molecular …

Cryo-soft X-ray tomography: using soft X-rays to explore the ultrastructure of whole cells

M Harkiolaki, MC Darrow, MC Spink… - Emerging topics in …, 2018 - portlandpress.com
Cryo-soft X-ray tomography is an imaging technique that addresses the need for mesoscale
imaging of cellular ultrastructure of relatively thick samples without the need for staining or …

Septins and K63 ubiquitin chains are present in separate bacterial microdomains during autophagy of entrapped Shigella

D Lobato-Márquez, JJ Conesa… - Journal of cell …, 2023 - journals.biologists.com
During host cell invasion, Shigella escapes to the cytosol and polymerizes actin for cell-to-
cell spread. To restrict cell-to-cell spread, host cells employ cell-autonomous immune …

The presence of bacteria within tissue provides insights into the pathogenesis of oral lichen planus

YS Choi, Y Kim, HJ Yoon, KJ Baek, J Alam, HK Park… - Scientific reports, 2016 - nature.com
Oral lichen planus (OLP) is a chronic T cell-mediated mucocutaneous disease of unknown
etiopathogenesis. Although various antigens have been considered, what actually triggers …

Laboratory cryo x-ray microscopy for 3D cell imaging

E Fogelqvist, M Kördel, V Carannante, B Önfelt… - Scientific reports, 2017 - nature.com
Water-window x-ray microscopy allows two-and three-dimensional (2D and 3D) imaging of
intact unstained cells in their cryofixed near-native state with unique contrast and high …

Across the spectrum: integrating multidimensional metal analytics for in situ metallomic imaging

TJ Stewart - Metallomics, 2019 - academic.oup.com
To know how much of a metal species is in a particular location within a biological context at
any given time is essential for understanding the intricate roles of metals in biology and is …

Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses

A Cruz-Adalia, G Ramirez-Santiago… - Nature …, 2017 - nature.com
Bacterial phagocytosis and antigen cross-presentation to activate CD8+ T cells are principal
functions of professional antigen presenting cells. However, conventional CD4+ T cells also …