Discovery of 9H-pyrimido [4, 5-b] indole derivatives as dual RET/TRKA inhibitors
Aberrant RET kinase signaling is activated in numerous cancers including lung, thyroid,
breast, pancreatic, and prostate. Recent approvals of selective RET inhibitors, pralsetinib …
breast, pancreatic, and prostate. Recent approvals of selective RET inhibitors, pralsetinib …
[HTML][HTML] Tyrosine Kinase Inhibitors and Thyroid Toxicity
S Mastrangelo, G Attina… - Biomedical and …, 2023 - biomedpharmajournal.org
Some multithyrosine kinase inhibitors have been reported to cause changes in thyroid
function. For the management of sunitinib-induced hypothyroidism, an evaluation of thyroid …
function. For the management of sunitinib-induced hypothyroidism, an evaluation of thyroid …