Cellular heterogeneity of mesenchymal stem/stromal cells in the bone marrow

Y Mabuchi, C Okawara, S Méndez-Ferrer… - Frontiers in cell and …, 2021 - frontiersin.org
Mesenchymal stem/stromal cells (MSCs) are present in various body tissues and help in
maintaining homeostasis. The stemness of MSCs has been evaluated in vitro. In addition …

Phenotypic screening of 1,953 FDA-approved drugs reveals 26 hits with potential for repurposing for Peyronie's disease

MM Ilg, AR Lapthorn, DJ Ralph, S Cellek - PLoS One, 2022 - journals.plos.org
Drug repurposing has been shown to bring safe medications to new patient populations, as
recently evidenced by the COVID-19 pandemic. We investigated whether we could use …

Cutaneous wound healing using polymeric surgical dressings based on chitosan, sodium hyaluronate and resveratrol. A preclinical experimental study

C Berce, MS Muresan, O Soritau, B Petrushev… - Colloids and Surfaces B …, 2018 - Elsevier
Wound healing is a complex and dynamic process that involves modifying the wound
environment depending on the patient's health status. Scar formation depends on many …

Transforming growth factor β‐mediated micromechanics modulates disease progression in primary myelofibrosis

P Teodorescu, S Pasca, A Jurj… - Journal of Cellular …, 2020 - Wiley Online Library
Primary myelofibrosis (PMF) is a Ph‐negative myeloproliferative neoplasm (MPN),
characterized by advanced bone marrow fibrosis and extramedullary haematopoiesis. The …

Mesenchymal stem cells in myeloproliferative disorders–focus on primary myelofibrosis

SE Selicean, C Tomuleasa, R Grewal… - Leukemia & …, 2019 - Taylor & Francis
Primary myelofibrosis (PMF) is the most aggressive Philadelphia-negative (Ph-)
myeloproliferative neoplasm (MPN), characterized by bone marrow (BM) insufficiency …

Ruxolitinib-conjugated gold nanoparticles for topical administration: An alternative for treating alopecia?

S Boca, C Berce, A Jurj, B Petrushev, L Pop… - Medical …, 2017 - Elsevier
Alopecia is a dermatological condition for which Janus kinase (JAK) inhibitors have recently
emerged as potential therapy options, but with limited practical use because of the systemic …

Persistent basophilia may suggest an “accelerated phase” in the evolution of CALR-positive primary myelofibrosis toward acute myeloid leukemia

J Dobrowolski, S Pasca, P Teodorescu… - Frontiers in …, 2019 - frontiersin.org
Basophils are white blood cells that play an important role in the human immune system.
These cells physiologically increase in number in immune response to certain allergies …

Cancer-associated fibroblasts in acute leukemia

L Gu, P Liao, H Liu - Frontiers in Oncology, 2022 - frontiersin.org
Although the prognosis for acute leukemia has greatly improved, treatment of
relapsed/refractory acute leukemia (R/R AL) remains challenging. Recently, increasing …

Overview of the side-effects of FDA-and/or EMA-approved targeted therapies for the treatment of hematological malignancies

C Constantinescu, S Pasca, AA Zimta, T Tat… - Journal of Clinical …, 2020 - mdpi.com
In the last decade there has been tremendous effort in offering better therapeutic
management strategies to patients with hematologic malignancies. These efforts have …

RETRACTED ARTICLE: Castleman's disease in the HIV-endemic setting

ER Mahroug, C Sher-Locketz… - Cancer Management …, 2018 - Taylor & Francis
Mahroug E, Sher-Locketz C, Desmirean M, et al. Cancer Manag Res. 2018; 10: 4553—
4563. The Editor-in-Chief and Publisher of Cancer Management and Research wish to …