From molecular pathogenesis to therapy: Unraveling non-coding RNAs/DNMT3A axis in human cancers
C Huang, SM Aghaei-Zarch - Biochemical Pharmacology, 2024 - Elsevier
Cancer is a comprehensive classification encompassing more than 100 forms of
malignancies that manifest in diverse tissues within the human body. Recent studies have …
malignancies that manifest in diverse tissues within the human body. Recent studies have …
MiRNAs as noninvasive biomarkers and therapeutic agents of pituitary adenomas
O Beylerli, NM Beeraka, I Gareev, V Pavlov… - International journal of …, 2020 - mdpi.com
Pituitary adenoma (PA) accounts for 10–15% of all intracranial neoplasms. Even though
most pituitary adenomas are benign, it is known that almost 35% of them exhibit an …
most pituitary adenomas are benign, it is known that almost 35% of them exhibit an …
CircNFIX promotes progression of glioma through regulating miR-378e/RPN2 axis
C Ding, Z Wu, H You, H Ge, S Zheng, Y Lin… - Journal of Experimental …, 2019 - Springer
Background Circular RNA nuclear factor IX (circNFIX) has been reported to play an
important role in glioma progression. However, the mechanism by which circNFIX …
important role in glioma progression. However, the mechanism by which circNFIX …
Targeted delivery of liposomal temozolomide enhanced anti-glioblastoma efficacy through ultrasound-mediated blood–brain barrier opening
Z Song, X Huang, J Wang, F Cai, P Zhao, F Yan - Pharmaceutics, 2021 - mdpi.com
Glioblastoma (GBM) is the commonest form of primary brain tumor in the central nervous
system, with median survival below 15 months and only a 25% two-year survival rate for …
system, with median survival below 15 months and only a 25% two-year survival rate for …
EGFR-targeted pentacyclic triterpene analogues for glioma therapy
Glioma, particularly its most malignant form, glioblastoma multiforme (GBM), is the most
common and aggressive malignant central nervous system tumor. The drawbacks of the …
common and aggressive malignant central nervous system tumor. The drawbacks of the …
Nanodisk-based glioma-targeted drug delivery enabled by a stable glycopeptide
Abstract Heptapeptide ATWLPPR (A7R) binds specifically to vascular endothelial growth
factor receptor 2 (VEGFR2) and neuropilin-1 (NRP-1) overexpressed in glioma cells …
factor receptor 2 (VEGFR2) and neuropilin-1 (NRP-1) overexpressed in glioma cells …
Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway
Y Ma, Z Di, Q Cao, W Xu, S Bi, J Yu, Y Shen… - Acta Pharmacologica …, 2020 - nature.com
Xanthatin is a natural sesquiterpene lactone purified from Xanthium strumarium L., which
has shown prominent antitumor activity against a variety of cancer cells. In the current study …
has shown prominent antitumor activity against a variety of cancer cells. In the current study …
[HTML][HTML] NLRP3 promotes glioma cell proliferation and invasion via the interleukin-1β/NF-κB p65 signals
L Xue, B Lu, B Gao, Y Shi, J Xu, R Yang, B Xu… - Oncology …, 2019 - ncbi.nlm.nih.gov
Because of the characteristics of high invasiveness, relapse, and poor prognosis, the
management of malignant gliomas has always been a great challenge. Nod-like receptor …
management of malignant gliomas has always been a great challenge. Nod-like receptor …
Xanthatin suppresses proliferation and tumorigenicity of glioma cells through autophagy inhibition via activation of the PI3K‐Akt–mTOR pathway
H Chen, T Zhu, X Huang, W Xu, Z Di… - Pharmacology …, 2023 - Wiley Online Library
Glioma is the most common and aggressive primary brain tumor in adults with high morbidity
and mortality. Rapid proliferation and diffuse migration are the main obstacles to successful …
and mortality. Rapid proliferation and diffuse migration are the main obstacles to successful …
Down-regulation of circ-PTN suppresses cell proliferation, invasion and glycolysis in glioma by regulating miR-432-5p/RAB10 axis
X Zhang, S Wang, G Lin, D Wang - Neuroscience Letters, 2020 - Elsevier
Abstract Background Circular RNAs (circRNAs) are related to the carcinogenesis of cancers,
including glioma. However, the role and mechanism of circRNA pleiotrophin (circ-PTN) …
including glioma. However, the role and mechanism of circRNA pleiotrophin (circ-PTN) …