Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …

Abstract Collagen alpha-1 (III) chain, also known as the alpha 1 chain of type III collagen, is
a protein that in humans is encoded by the COL3A1 gene. Three alpha 1 chains are …

Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood
vessel degenerates, leading to dilation and eventually vessel wall rupture. Recently, it was …

Aortic aneurysm is a chronic disease characterized by localized expansion of the aorta,
including the ascending aorta, arch, descending aorta, and abdominal aorta. Although aortic …

Background: Large-scale human and mechanistic mouse studies indicate a strong
relationship between the microbiome-dependent metabolite trimethylamine N-oxide (TMAO) …

An abdominal aortic aneurysm (AAA) is a localized dilatation of the infrarenal aorta. AAA is a
multifactorial disease, and genetic and environmental factors play a part; smoking, male sex …

Objective: Macrophages are immune cells, capable to remodel the extracellular matrix,
which can harbor extracellular DNA incorporated into neutrophil extracellular traps (NETs) …

Background The early survival advantage of endovascular aneurysm repair (EVAR)
compared with open repair reverses over time, possibly because of higher rates of …

Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …

To determine the roles of endoplasmic reticulum (ER) stress and trained immunity, we
performed transcriptome analyses on the thoracic aorta (TA) and abdominal aorta (AA) from …