Early detection of neurodegenerative disorders would provide clues to the underlying
pathobiology of these diseases and would enable more effective diagnosis and treatment of …

Background The majority of patients with Parkinson's disease (PD) have handwriting
abnormalities. Micrographia (abnormally small letter size) is the most commonly reported …

Background Parkinson's disease (PD) is a progressive neurodegenerative disease with no
cure and few treatment options. Its incidence is increasing due to aging populations, longer …

Background Isolated rest tremor, which is observed in some patients with essential tremor
(ET), poses a diagnostic challenge. The phenomenon has been examined in few studies …

The various forms of tremor are now classified in two axes: clinical characteristics (axis 1)
and etiology (axis 2). Electrophysiology is an extension of the clinical exam …

Effective management and development of new treatment strategies of motor symptoms in
Parkinson's disease (PD) largely depend on clinical rating instruments like the Unified PD …

Background Tremors are among the most common movement disorders. As there can be
considerable variability in the manner in which clinicians assess tremor, objective …

Studying the effects of neurodegeneration on handwriting has emerged as an
interdisciplinary research topic and has attracted considerable interest from psychologists to …

The monitoring of the progression of Parkinson's disease (PD) is held on frequently in the
clinic and an inconvenient and time-consuming process since PD is generally observed …

Parkinson's disease (PD) is a degenerative disease that affects the motor system, which may
cause slowness of the speech and the movements, and the anomaly of writing abilities due …