The developmental and epileptic encephalopathies encompass a group of rare syndromes
characterised by severe drug-resistant epilepsy with onset in childhood and significant …

Impairments in cognition are common in epilepsy and may be caused or exacerbated by
antiseizure medications (ASMs). Positive effects on cognition may also be seen with some …

Abstract Lennox-Gastaut syndrome (LGS), a childhood-onset severe developmental and
epileptic encephalopathy (DEE), is an entity that encompasses a heterogenous group of …

Managing epilepsy in people with an intellectual disability remains a therapeutic challenge
and must take into account additional issues such as diagnostic difficulties and frequent …

Objectives The aim of our study was to evaluate the effectiveness and tolerability of
perampanel (PER) as first add-on and as second line monotherapy in subjects with …

Introduction: The aim of this study was to identify the presence of emotional and behavioral
symptoms in children and adolescents with epilepsy, to measure the stress levels in their …

Lennox-Gastaut syndrome (LGS) is a severe, chronic, complex form of early childhood-onset
epilepsy characterized by multiple seizure types, generalized slow (≤ 2.5 Hz) spike-and …

This study aims to describe the main cognitive and behavioral comorbidities of Dravet
syndrome (DS) and Lennox–Gastaut syndrome (LGS), their impact on the health-related …

Introduction The goal of the present study was to comparatively analyze Social Cognition
skills in a pediatric population diagnosed with Migraine or Epilepsy, compared to Typically …

Introduction Rufinamide is an antiseizure medication that acts through sodium channels and
is found to be efficacious in patients with Lennox Gastaut syndrome (LGS). However, no …