Psychobehavioural and cognitive adverse events of anti-seizure medications for the treatment of developmental and epileptic encephalopathies
A Strzelczyk, S Schubert-Bast - CNS drugs, 2022 - Springer
The developmental and epileptic encephalopathies encompass a group of rare syndromes
characterised by severe drug-resistant epilepsy with onset in childhood and significant …
characterised by severe drug-resistant epilepsy with onset in childhood and significant …
Neurocognitive effects of antiseizure medications in children and adolescents with epilepsy
FMC Besag, MJ Vasey - Pediatric Drugs, 2021 - Springer
Impairments in cognition are common in epilepsy and may be caused or exacerbated by
antiseizure medications (ASMs). Positive effects on cognition may also be seen with some …
antiseizure medications (ASMs). Positive effects on cognition may also be seen with some …
Expanding the treatment landscape for Lennox-Gastaut syndrome: current and future strategies
A Strzelczyk, S Schubert-Bast - CNS drugs, 2021 - Springer
Abstract Lennox-Gastaut syndrome (LGS), a childhood-onset severe developmental and
epileptic encephalopathy (DEE), is an entity that encompasses a heterogenous group of …
epileptic encephalopathy (DEE), is an entity that encompasses a heterogenous group of …
[HTML][HTML] Epilepsy and cognitive impairment in childhood and adolescence: a mini-review
FF Operto, GMG Pastorino, A Viggiano… - Current …, 2023 - ncbi.nlm.nih.gov
Managing epilepsy in people with an intellectual disability remains a therapeutic challenge
and must take into account additional issues such as diagnostic difficulties and frequent …
and must take into account additional issues such as diagnostic difficulties and frequent …
Perampanel and childhood absence epilepsy: A real life experience
FF Operto, A Orsini, G Sica, C Scuoppo… - Frontiers in …, 2022 - frontiersin.org
Objectives The aim of our study was to evaluate the effectiveness and tolerability of
perampanel (PER) as first add-on and as second line monotherapy in subjects with …
perampanel (PER) as first add-on and as second line monotherapy in subjects with …
Psychiatric symptoms and parental stress in children and adolescents with epilepsy
FF Operto, GMG Pastorino, F Pippa… - Frontiers in …, 2021 - frontiersin.org
Introduction: The aim of this study was to identify the presence of emotional and behavioral
symptoms in children and adolescents with epilepsy, to measure the stress levels in their …
symptoms in children and adolescents with epilepsy, to measure the stress levels in their …
[HTML][HTML] Proposed anti-seizure medication combinations with rufinamide in the treatment of Lennox-Gastaut syndrome: Narrative review and expert opinion
R Sankar, M Chez, JE Pina-Garza… - … : European Journal of …, 2023 - Elsevier
Lennox-Gastaut syndrome (LGS) is a severe, chronic, complex form of early childhood-onset
epilepsy characterized by multiple seizure types, generalized slow (≤ 2.5 Hz) spike-and …
epilepsy characterized by multiple seizure types, generalized slow (≤ 2.5 Hz) spike-and …
Comorbidities in Dravet syndrome and Lennox–Gastaut syndrome
F Marchese, S Cappelletti, M Filippini, CA Guido… - SN Comprehensive …, 2021 - Springer
This study aims to describe the main cognitive and behavioral comorbidities of Dravet
syndrome (DS) and Lennox–Gastaut syndrome (LGS), their impact on the health-related …
syndrome (DS) and Lennox–Gastaut syndrome (LGS), their impact on the health-related …
Migraine and epilepsy: social cognition skills in pediatric population
FF Operto, C Scuoppo, C Padovano, V Vivenzio… - European Journal of …, 2022 - Elsevier
Introduction The goal of the present study was to comparatively analyze Social Cognition
skills in a pediatric population diagnosed with Migraine or Epilepsy, compared to Typically …
skills in a pediatric population diagnosed with Migraine or Epilepsy, compared to Typically …
[HTML][HTML] Efficacy and safety of rufinamide as adjunctive therapy in patients with Lennox Gastaut syndrome: A systematic review and Meta-analysis
Introduction Rufinamide is an antiseizure medication that acts through sodium channels and
is found to be efficacious in patients with Lennox Gastaut syndrome (LGS). However, no …
is found to be efficacious in patients with Lennox Gastaut syndrome (LGS). However, no …