[HTML][HTML] Emerging roles of lysophospholipids in health and disease

ST Tan, T Ramesh, XR Toh, LN Nguyen - Progress in Lipid Research, 2020 - Elsevier
Lipids are abundant and play essential roles in human health and disease. The main
functions of lipids are building blocks for membrane biogenesis. However, lipids are also …

[HTML][HTML] Role of lysophosphatidic acid and its receptors in health and disease: novel therapeutic strategies

LHM Geraldo, TCLS Spohr, RF Amaral… - Signal transduction and …, 2021 - nature.com
Lysophosphatidic acid (LPA) is an abundant bioactive phospholipid, with multiple functions
both in development and in pathological conditions. Here, we review the literature about the …

LPA receptors: subtypes and biological actions

JW Choi, DR Herr, K Noguchi, YC Yung… - Annual review of …, 2010 - annualreviews.org
Lysophosphatidic acid (LPA) is a small, ubiquitous phospholipid that acts as an extracellular
signaling molecule by binding to and activating at least five known G protein–coupled …

Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples

X Han, RW Gross - Mass spectrometry reviews, 2005 - Wiley Online Library
Lipidomics, after genomics and proteomics, is a newly and rapidly expanding research field
that studies cellular lipidomes and the organizational hierarchy of lipid and protein …

Autotaxin derived from lipoprotein (a) and valve interstitial cells promotes inflammation and mineralization of the aortic valve

R Bouchareb, A Mahmut, MJ Nsaibia, MC Boulanger… - Circulation, 2015 - Am Heart Assoc
Background—Mendelian randomization studies have highlighted that lipoprotein (a)[Lp (a)]
was associated with calcific aortic valve disease (CAVD). Lp (a) transports oxidized …

Electrospray mass spectrometry of phospholipids

M Pulfer, RC Murphy - Mass spectrometry reviews, 2003 - Wiley Online Library
Abstract I. Introduction 332 II. Techniques and Methods 334 A. Sample Preparation 334 B.
ESI‐MS/MS 336 1. Glycerophosphocholine (GPCho) Lipids 336 2. Sphingomyelin 341 3 …

[HTML][HTML] The BUME method: A novel automated chloroform-free 96-well total lipid extraction method for blood plasma [S]

L Löfgren, M Ståhlman, GB Forsberg, S Saarinen… - Journal of lipid …, 2012 - ASBMB
Lipid extraction from biological samples is a critical and often tedious preanalytical step in
lipid research. Primarily on the basis of automation criteria, we have developed the BUME …

Lysophospholipid receptors: signaling and biology

I Ishii, N Fukushima, X Ye, J Chun - Annual review of …, 2004 - annualreviews.org
▪ Abstract Lysophospholipids (LPs), such as lysophosphatidic acid and sphingosine 1-
phosphate, are membrane-derived bioactive lipid mediators. LPs can affect fundamental …

[HTML][HTML] The BUME method: a new rapid and simple chloroform-free method for total lipid extraction of animal tissue

L Löfgren, GB Forsberg, M Ståhlman - Scientific reports, 2016 - nature.com
In this study we present a simple and rapid method for tissue lipid extraction. Snap-frozen
tissue (15–150 mg) is collected in 2 ml homogenization tubes. 500 μl BUME mixture …

[HTML][HTML] Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family

K Noguchi, S Ishii, T Shimizu - Journal of Biological Chemistry, 2003 - ASBMB
Lysophosphatidic acid (LPA) is a bioactive lipid mediator with diverse physiological and
pathological actions on many types of cells. LPA has been widely considered to elicit its …