The human FcγRII (CD32) family of leukocyte FcR in health and disease

JC Anania, AM Chenoweth, BD Wines… - Frontiers in …, 2019 - frontiersin.org
FcγRs have been the focus of extensive research due to their key role linking innate and
humoral immunity and their implication in both inflammatory and infectious disease. Within …

DNA methylation biomarkers of future health outcomes in children

S Shanthikumar, MR Neeland, J Maksimovic… - Molecular and Cellular …, 2020 - Springer
Biomarkers which predict future health outcomes are key to the goals of precision health.
Such biomarkers do not have to be involved in the causal pathway of a disease, and their …

Interleukin-1 beta–mediated sex differences in Kawasaki disease vasculitis development and response to treatment

RA Porritt, JL Markman, D Maruyama… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Kawasaki disease (KD) is the leading cause of acute vasculitis and acquired
heart disease in children in developed countries. Notably, KD is more prevalent in males …

Male-specific association of the FCGR2A His167Arg polymorphism with Kawasaki disease

YC Kwon, JJ Kim, SW Yun, JJ Yu, KL Yoon, KY Lee… - PLoS …, 2017 - journals.plos.org
Kawasaki disease (KD) is an acute systemic vasculitis that can potentially cause coronary
artery aneurysms in some children. KD occurs approximately 1.5 times more frequently in …

Prediction for intravenous immunoglobulin resistance by using weighted genetic risk score identified from genome-wide association study in Kawasaki disease

HC Kuo, HSC Wong, WP Chang, BK Chen… - Circulation …, 2017 - Am Heart Assoc
Background—Intravenous immunoglobulin (IVIG) is the treatment of choice in Kawasaki
disease (KD). IVIG is used to prevent cardiovascular complications related to KD. However …

Major methylation alterations on the CpG markers of inflammatory immune associated genes after IVIG treatment in Kawasaki disease

SC Li, WC Chan, YH Huang, MMH Guo, HR Yu… - BMC medical …, 2016 - Springer
Background Kawasaki disease (KD) is an autoimmune disease preferentially attacking
children younger than five years worldwide. So far, the principal treatment to KD is the …

The effect of FcγRIIA and FcγRIIB on coronary artery lesion formation and intravenous immunoglobulin treatment responses in children with Kawasaki disease

LS Chang, MH Lo, SC Li, MY Yang, KS Hsieh… - Oncotarget, 2016 - pmc.ncbi.nlm.nih.gov
Previous research has found patients with the FcγRIIIB NA1 variant having increased risk of
intravenous immunoglobulin (IVIG) resistance in Kawasaki disease (KD). Our previous …

Risk-prediction models for intravenous immunoglobulin resistance in Kawasaki disease: Risk-of-Bias Assessment using PROBAST

S Wang, H Huang, M Hou, Q Xu, W Qian, Y Tang… - Pediatric …, 2023 - nature.com
Background The prediction model of intravenous immunoglobulin (IVIG) resistance in
Kawasaki disease can calculate the probability of IVIG resistance and provide a basis for …

Promising biomarkers of kawasaki disease: markers that aid in diagnosis

MMH Guo, HC Kuo - Expert Review of Molecular Diagnostics, 2024 - Taylor & Francis
Introduction Currently the diagnosis of Kawasaki disease is still heavily reliant on clinical
criteria which may be subject to interpretation or mimic other common febrile diseases of …

[HTML][HTML] Identification of aberrantly methylated differentially expressed genes targeted by differentially expressed miRNA in osteosarcoma

TX Wang, WL Tan, JC Huang, ZF Cui… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Osteosarcoma (OS) is the most common primary bone tumors diagnosed in
children and adolescents. Recent studies have shown a prognostic role of DNA methylation …