Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

Mitochondria control cellular fate by various mechanisms and are key drivers of cellular
metabolism. Although the main function of mitochondria is energy production, they are also …

Biomarker discovery and implementation are at the forefront of the precision medicine
movement. Modern advances in the field of metabolomics afford the opportunity to readily …

Comparing energy metabolism in human skeletal muscle and primary skeletal muscle cells
in obesity, while focusing on glucose and fatty acid metabolism, shows many common …

Small molecule tyrosine kinase inhibitors (TKIs) are widely used as anticancer drugs
approved by US FDA. However, the toxicities of TKIs to multiple organs have greatly limited …

On this 100 th anniversary of the discovery of insulin, we recognize the critical role that
adipocytes, which are exquisitely responsive to insulin, have played in determining the …

Carnitine metabolism is thought to be negatively correlated with the progression of
hepatocellular carcinoma (HCC) and the specific molecular mechanism is yet to be fully …

Glucose, fatty acids, and amino acids among others are oxidized to generate adenosine
triphosphate (ATP). These fuels are supplied from the environment (through food intake) and …

1H‐MR spectroscopy of skeletal muscle provides insight into metabolism that is not
available noninvasively by other methods. The recommendations given in this article are …

Objective SGLT2 inhibitors increase urinary glucose excretion and have beneficial effects on
cardiovascular and renal outcomes; the underlying mechanism may be metabolic …