Tendon injury: from biology to tendon repair

G Nourissat, F Berenbaum, D Duprez - Nature Reviews Rheumatology, 2015 - nature.com
Tendon is a crucial component of the musculoskeletal system. Tendons connect muscle to
bone and transmit forces to produce motion. Chronic and acute tendon injuries are very …

The impact of loading, unloading, ageing and injury on the human tendon

SP Magnusson, M Kjaer - The Journal of physiology, 2019 - Wiley Online Library
A tendon transfers force from the contracting muscle to the skeletal system to produce
movement and is therefore a crucial component of the entire muscle‐tendon complex and its …

The role of mechanical loading in tendon development, maintenance, injury, and repair

MT Galloway, AL Lalley, JT Shearn - JBJS, 2013 - journals.lww.com
The Role of Mechanical Loading in Tendon Development, Mainte... : JBJS The Role of
Mechanical Loading in Tendon Development, Maintenance, Injury, and Repair : JBJS JBJS …

PRICE needs updating, should we call the POLICE?

CM Bleakley, P Glasgow, DC MacAuley - British journal of sports …, 2012 - bjsm.bmj.com
CM Bleakley, 1, 3 P Glasgow, 2, 3 DC MacAuley 4 adverse changes to tissue biomechanics
and morphology. Progressive mechanical loading is more likely to restore the strength and …

Tendon tissue engineering: An overview of biologics to promote tendon healing and repair

V Citro, M Clerici, AR Boccaccini… - Journal of tissue …, 2023 - journals.sagepub.com
Tendons are dense connective tissues with a hierarchical polarized structure that respond to
and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion …

Tendon development and musculoskeletal assembly: emerging roles for the extracellular matrix

A Subramanian, TF Schilling - Development, 2015 - journals.biologists.com
Tendons and ligaments are extracellular matrix (ECM)-rich structures that interconnect
muscles and bones. Recent work has shown how tendon fibroblasts (tenocytes) interact with …

EGR1 transcription factor is a multifaceted regulator of matrix production in tendons and other connective tissues

E Havis, D Duprez - International journal of molecular sciences, 2020 - mdpi.com
Although the transcription factor EGR1 is known as NGF1-A, TIS8, Krox24, zif/268, and
ZENK, it still has many fewer names than biological functions. A broad range of signals …

The Effects of Mechanical Loading on Tendons - An In Vivo and In Vitro Model Study

J Zhang, JHC Wang - PloS one, 2013 - journals.plos.org
Mechanical loading constantly acts on tendons, and a better understanding of its effects on
the tendons is essential to gain more insights into tendon patho-physiology. This study aims …

Mechanical force regulates tendon extracellular matrix organization and tenocyte morphogenesis through TGFbeta signaling

A Subramanian, LF Kanzaki, JL Galloway, TF Schilling - Elife, 2018 - elifesciences.org
Mechanical forces between cells and extracellular matrix (ECM) influence cell shape and
function. Tendons are ECM-rich tissues connecting muscles with bones that bear extreme …

[HTML][HTML] The Achilles tendon: fundamental properties and mechanisms governing healing

BR Freedman, JA Gordon… - Muscles, ligaments and …, 2014 - ncbi.nlm.nih.gov
This review highlights recent research on Achilles tendon healing, and comments on the
current clinical controversy surrounding the diagnosis and treatment of injury. The processes …