This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2017. Other selected articles can be found online at http://ccforum …

Mechanical ventilation induces a number of systemic responses for which the brain plays an
essential role. During the last decade, substantial evidence has emerged showing that the …

Previous studies have identified that dexmedetomidine (DEX) treatment can ameliorate the
acute lung injury (ALI) induced by lipopolysaccharide and ischemia-reperfusion. However …

Background: Propofol and sevoflurane are widely used in clinical anesthesia, and both have
been reported to exert a protective effect in organ ischemia/reperfusion (IR). This study aims …

BACKGROUND: Administering anesthetics to the obese population requires caution
because of a variety of reasons including possible interactions with the inflammatory …

Background We used a two-hit lung injury rat model that involves mechanical ventilation
(MV) following lipopolysaccharide exposure to investigate the effects of propofol on the …

Anesthesiologists should take into consideration the immunomodulatory properties of
anesthetic agents in addition to their hemodynamic, neuroprotective, and other impacts. In …

Ventilator-induced lung injury (VILI) causes problems during acute lung injury treatment, and
propofol is a well-known drug to prevent VILI. Herein, we discussed how propofol protects …

Purpose The aim of the present article was to briefly summarize current knowledge about
the immunomodulatory effects of general anesthetics and the possible clinical effects of this …

Methods: In this prospective randomized trial, 52 children were randomly allocated to Group
B who received intraperitoneal bupivacaine 0.25%(2 mg/kg) or Group BD who received …