Obesity is a multi-factorial disorder, which is often associated with many other significant
diseases such as diabetes, hypertension and other cardiovascular diseases, osteoarthritis …

Background The primary goal of weight loss is to prevent or reduce obesity-associated
morbidity and mortality by improving cardiovascular and metabolic risk factors. We …

Obesity is one of the most serious public health problems in the 21st century that may lead to
many comorbidities such as type-2 diabetes, cardiovascular diseases, and cancer. Current …

Obesity is an increasingly prevalent human condition in developed societies. Despite major
progress in the understanding of the molecular mechanisms leading to obesity, no safe and …

The present study examined the biological potential and phytochemicals of Sophora mollis,
Mucuna pruriens, and Indigofera atropurpurea methanolic leaf extracts. In vitro anti …

Orexin-A and-B are neuropeptides mainly expressed in the lateral hypothalamic area (LHA).
A role for orexins was first demonstrated in the regulation of feeding behaviour …

β3-Adrenoceptor agonists are very effective thermogenic anti-obesity and insulin-sensitising
agents in rodents. Their main sites of action are white and brown adipose tissue, and …

▪ Abstract For a long time neural and endocrine messages were studied for their impact on
adipocyte metabolism and control of storage/release of fatty acids. In fact, bidirectional …

Neuropeptides terminating in‐Arg‐Phe‐NH2 (‐RFamide) were first discovered in molluscan
nervous systems, but were soon recognized to occur widely throughout the invertebrates …

Pharmacotherapy for the management of obesity is primarily aimed at weight loss, weight
loss maintenance and risk reduction, and has included thyroid hormone, amphetamines …