Maternal microbiota, early life colonization and breast milk drive immune development in the newborn

C Kalbermatter, N Fernandez Trigo… - Frontiers in …, 2021 - frontiersin.org
The innate immune system is the oldest protection strategy that is conserved across all
organisms. Although having an unspecific action, it is the first and fastest defense …

Human breast milk: from food to active immune response with disease protection in infants and mothers

GAG Lokossou, L Kouakanou, A Schumacher… - Frontiers in …, 2022 - frontiersin.org
Breastfeeding is associated with long-term wellbeing including low risks of infectious
diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases …

Cells of human breast milk

M Witkowska-Zimny, E Kaminska-El-Hassan - Cellular & molecular biology …, 2017 - Springer
Human milk is a complex fluid that has developed to satisfy the nutritional requirements of
infants. In addition to proteins, lipids, carbohydrates and other biologically active …

A review of the immunomodulating components of maternal breast milk and protection against necrotizing enterocolitis

LS Nolan, OB Parks, M Good - Nutrients, 2019 - mdpi.com
Breast milk contains immunomodulating components that are beneficial to newborns during
maturation of their immune system. Human breast milk composition is influenced by an …

Lactation-associated macrophages exist in murine mammary tissue and human milk

D Cansever, E Petrova, S Krishnarajah, C Mussak… - Nature …, 2023 - nature.com
Macrophages are involved in immune defense, organogenesis and tissue homeostasis.
Macrophages contribute to the different phases of mammary gland remodeling during …

Breastfeeding and autoimmunity: Programing health from the beginning

V Vieira Borba, K Sharif… - American Journal of …, 2018 - Wiley Online Library
Breast milk is not only a completely adapted nutrition source for the newborn but also an
impressive array of immune‐active molecules that afford protection against infections and …

Comprehensive proteomic analysis of human milk-derived extracellular vesicles unveils a novel functional proteome distinct from other milk components

MJC van Herwijnen, MI Zonneveld, S Goerdayal… - Molecular & Cellular …, 2016 - ASBMB
Breast milk contains several macromolecular components with distinctive functions, whereby
milk fat globules and casein micelles mainly provide nutrition to the newborn, and whey …

The gut‒breast axis: programming health for life

JM Rodríguez, L Fernández, V Verhasselt - Nutrients, 2021 - mdpi.com
The gut is a pivotal organ in health and disease. The events that take place in the gut during
early life contribute to the programming, shaping and tuning of distant organs, having …

Breast milk and the importance of chrononutrition

MD Caba-Flores, A Ramos-Ligonio… - Frontiers in …, 2022 - frontiersin.org
During pregnancy the human fetus receives timed cues from the circadian rhythms of
temperature, metabolites, and hormones from the mother. This influence is interrupted after …

Maternal leukocytes and infant immune programming during breastfeeding

A Laouar - Trends in Immunology, 2020 - cell.com
The fetal immune system develops in a rather sterile environment relative to the outside
world and, therefore, lacks antigenic education. Soon after birth, the newborn is exposed to …