A review of SARS-CoV-2 drug repurposing: Databases and machine learning models

M Elkashlan, RM Ahmad, M Hajar, F Al Jasmi… - Frontiers in …, 2023 - frontiersin.org
The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2)
posed a serious worldwide threat and emphasized the urgency to find efficient solutions to …

Prospects of novel and repurposed immunomodulatory drugs against acute respiratory distress syndrome (ARDS) associated with covid-19 disease

SS Nayak, A Naidu, SL Sudhakaran, S Vino… - Journal of personalized …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is intricately linked with SARS-CoV-2-
associated disease severity and mortality, especially in patients with co-morbidities. Lung …

Using informative features in machine learning based method for COVID-19 drug repurposing

R Aghdam, M Habibi, G Taheri - Journal of cheminformatics, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by a novel virus named Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). This virus induced a large …

New life of an old drug: Caffeine as a modulator of antibacterial activity of commonly used antibiotics

A Woziwodzka, M Krychowiak-Maśnicka, G Gołuński… - Pharmaceuticals, 2022 - mdpi.com
With the rapid and continuous emergence of antimicrobial resistance, bacterial infections
became a significant global healthcare concern. One of the proposed strategies to combat …

TiO2/Arabic Gum for Degradation of Pollutants in Water

A Lopes, FP Araújo, D Damasceno, LMC Honório… - Sustainability, 2023 - mdpi.com
Emerging contaminants and pollution are environmental problems threatening public health.
Antibiotic ciprofloxacin and methylene blue dye are pollutants frequently detected in water …

Role of different types of RNA molecules in the severity prediction of SARS-CoV-2 patients

P Jeyananthan - Pathology-Research and Practice, 2023 - Elsevier
SARS-CoV-2 pandemic is the current threat of the world with enormous number of
deceases. As most of the countries have constraints on resources, particularly for intensive …

Drug repurposing against main protease and RNA-dependent RNA polymerase of SARS-CoV-2 using molecular docking, MM-GBSA calculations and molecular …

AO Mohammed, MI Abo-Idrees, AA Makki… - Structural Chemistry, 2022 - Springer
A virus called severe acute respiratory distress syndrome coronavirus type 2 (SARS‐CoV‐2)
is the causing organism of coronavirus disease 2019 (COVID-19), which has severely …

Network controllability solutions for computational drug repurposing using genetic algorithms

VB Popescu, K Kanhaiya, DI Năstac, E Czeizler… - Scientific reports, 2022 - nature.com
Control theory has seen recently impactful applications in network science, especially in
connections with applications in network medicine. A key topic of research is that of finding …

New Revolution for Quality Control of TCM in Industry 4.0: Focus on Artificial Intelligence and Bioinformatics

Y Li, J Fan, X Cheng, H Jin, Y Wang, F Wei, F An… - TrAC Trends in …, 2024 - Elsevier
Quality controllability of traditional Chinese medicine (TCM) is the cornerstone for safety and
efficacy. Under Industry 4.0, what are the great transformations of quality control for TCM in …

Discovery of common molecular signatures and drug repurposing for COVID-19/Asthma comorbidity: ACE2 and multi-partite networks

J Xu, R Abdulsalam Khaleel, HK Zaidan… - Cell Cycle, 2024 - Taylor & Francis
ABSTRACT Angiotensin-converting enzyme 2 (ACE2) is identified as the functional receptor
for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of …