Electrochemical functionalization of imidazopyridine and indazole: An overview
Electrochemical synthesis offers a mild, simple, and efficient tool for the preparation of
interesting and useful molecules, thus eluding severe chemical oxidizing and reducing …
interesting and useful molecules, thus eluding severe chemical oxidizing and reducing …
Synthesis and site selective C–H functionalization of imidazo-[1, 2-a] pyridines
Imidazo [1, 2-a] pyridine has gained much interest in the field of drug development because
of its strong medicinal properties, therefore the discovery of novel methods for its synthesis …
of its strong medicinal properties, therefore the discovery of novel methods for its synthesis …
Four-component synthesis of 3-aminomethylated imidazoheterocycles in EtOH under catalyst-free, oxidant-free and mild conditions
QW Gui, BB Wang, S Zhu, FL Li, MX Zhu, M Yi… - Green …, 2021 - pubs.rsc.org
With green ethanol as the sole solvent, various 3-aminomethylated imidazoheterocycles
were efficiently synthesized in one step through a four-component reaction of equimolar …
were efficiently synthesized in one step through a four-component reaction of equimolar …
Synthesis and biological activities of bicyclic pyridines integrated steroid hybrid
MM Hammouda, KM Elattar, MM Rashed, AMA Osman - Steroids, 2023 - Elsevier
Reports on structural modification of heterosteroids through various reactions, and
developed synthetic routes have considerably increased over the last decade. The present …
developed synthetic routes have considerably increased over the last decade. The present …
Discovery of highly potent proapoptotic antiestrogens in a series of androst-5, 16-dienes D-modified with imidazole-annulated pendants
V Birukova, A Scherbakov, A Ilina, D Salnikova… - The Journal of Steroid …, 2023 - Elsevier
Heterocyclic derivatives of steroid hormones are potent anticancer agents, which are used in
the chemotherapy of breast and prostate cancers. Here, we describe a novel series of …
the chemotherapy of breast and prostate cancers. Here, we describe a novel series of …
Ortho C−H Functionalization of 2‐Arylimidazo[1,2‐a]pyridines
C− H activation and functionalization is quite promising in recent days as the strategy offers
a go‐to general method for different bond formations and hence grants synthetic versatility …
a go‐to general method for different bond formations and hence grants synthetic versatility …
Recent advances in carbosilylation of alkenes and alkynes
Alkene and alkyne difunctionalization is a flexible process that allows the construction of two
functional groups simultaneously in one step. On the other hand, carbosilylation, an …
functional groups simultaneously in one step. On the other hand, carbosilylation, an …
Apoptosis oxidative damage‐mediated and antiproliferative effect of selenylated imidazo[1,2‐a]pyridines on hepatocellular carcinoma HepG2 cells and in vivo
Abstract Imidazo [1, 2‐a] pyridines (IP) and organoselenium compounds have been widely
exploited in medicinal chemistry due to their pharmacological activities. Hepatocellular …
exploited in medicinal chemistry due to their pharmacological activities. Hepatocellular …
Difluoroborate complexes in the synthesis of heterocyclic (13α)-estrone derivatives modified at the A-ring
AA Sukhanova, MA Prezent, AN Fakhrutdinov… - Russian Chemical …, 2023 - Springer
An efficient synthesis of (13α)-estrone derivatives containing pyran, isoxazole, or pyrazole
moieties on the A-ring was performed based on difluoroborate complexes using the chelate …
moieties on the A-ring was performed based on difluoroborate complexes using the chelate …
Synthesis of Unsymmetrical Biheteroarenes via Dehydrogenative and Decarboxylative Coupling: a Decade Update
The design and development of robust and efficient methods for installing one heterocycle
with another is endowed as a ubiquitous and powerful synthetic strategy to access complex …
with another is endowed as a ubiquitous and powerful synthetic strategy to access complex …