An amuse-bouche of stem cell regulation: Underlying principles and mechanisms from adult Drosophila intestinal stem cells
B Boumard, AJ Bardin - Current Opinion in Cell Biology, 2021 - Elsevier
Stem cells have essential functions in the development and maintenance of our organs.
Improper regulation of adult stem cells and tissue homeostasis can result in cancers and …
Improper regulation of adult stem cells and tissue homeostasis can result in cancers and …
Tissue homeostasis and non-homeostasis: from cell life cycles to organ states
LE O'Brien - Annual review of cell and developmental biology, 2022 - annualreviews.org
Although tissue homeostasis—the steady state—implies stability, our organs are in a state of
continual, large-scale cellular flux. This flux underpins an organ's ability to homeostatically …
continual, large-scale cellular flux. This flux underpins an organ's ability to homeostatically …
Cholinergic neurons trigger epithelial Ca2+ currents to heal the gut
A fundamental and unresolved question in regenerative biology is how tissues return to
homeostasis after injury. Answering this question is essential for understanding the …
homeostasis after injury. Answering this question is essential for understanding the …
The cellular diversity and transcription factor code of Drosophila enteroendocrine cells
Enteroendocrine cells (EEs) in the intestinal epithelium have important endocrine functions,
yet this cell lineage exhibits great local and regional variations that have hampered detailed …
yet this cell lineage exhibits great local and regional variations that have hampered detailed …
The Drosophila tumor necrosis factor receptor, Wengen, couples energy expenditure with gut immunity
R Loudhaief, R Jneid, CF Christensen, DJ Mackay… - Science …, 2023 - science.org
It is well established that tumor necrosis factor (TNF) plays an instrumental role in
orchestrating the metabolic disorders associated with late stages of cancers. However, it is …
orchestrating the metabolic disorders associated with late stages of cancers. However, it is …
Bilberry (Vaccinium myrtillus L.) extracts comparative analysis regarding their phytonutrient profiles, antioxidant capacity along with the in vivo rescue effects tested on …
Bilberries (Vaccinium myrtillus L.) have been reported to hold a plentitude of health-
promoting properties beyond basic nutrition, mainly attributed to their anthocyanin content …
promoting properties beyond basic nutrition, mainly attributed to their anthocyanin content …
Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
In response to physiological demand, the pituitary gland generates new hormone-secreting
cells from committed progenitor cells throughout life. It remains unclear to what extent …
cells from committed progenitor cells throughout life. It remains unclear to what extent …
Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12
Transforming growth factor β (TGFβ) pathway is a master regulator of cell proliferation,
differentiation, and death. Deregulation of TGFβ signalling is well established in several …
differentiation, and death. Deregulation of TGFβ signalling is well established in several …
The septate junction protein Tsp2A restricts intestinal stem cell activity via endocytic regulation of aPKC and Hippo signaling
Hippo signaling and the activity of its transcriptional coactivator, Yorkie (Yki), are conserved
and crucial regulators of tissue homeostasis. In the Drosophila midgut, after tissue damage …
and crucial regulators of tissue homeostasis. In the Drosophila midgut, after tissue damage …
Drosophila TNF/TNFRs: At the crossroad between metabolism, immunity, and tissue homeostasis
J Colombani, DS Andersen - FEBS letters, 2023 - Wiley Online Library
Tumor necrosis factor (TNF)‐α is a highly conserved proinflammatory cytokine with important
functions in immunity, tissue repair, and cellular homeostasis. Due to the simplicity of the …
functions in immunity, tissue repair, and cellular homeostasis. Due to the simplicity of the …