The magic of bicelles lights up membrane protein structure
UHN Dürr, M Gildenberg, A Ramamoorthy - Chemical reviews, 2012 - ACS Publications
Biological membranes and membrane proteins, responsible for numerous exciting
biological processes, present one of the paramount challenges in biophysics today …
biological processes, present one of the paramount challenges in biophysics today …
[HTML][HTML] Choosing membrane mimetics for NMR structural studies of transmembrane proteins
DE Warschawski, AA Arnold, M Beaugrand… - … et Biophysica Acta (BBA …, 2011 - Elsevier
The native environment of membrane proteins is complex and scientists have felt the need
to simplify it to reduce the number of varying parameters. However, experimental problems …
to simplify it to reduce the number of varying parameters. However, experimental problems …
When detergent meets bilayer: birth and coming of age of lipid bicelles
UHN Dürr, R Soong, A Ramamoorthy - Progress in nuclear magnetic …, 2013 - Elsevier
► Lipid bicelles have matured to full membership in the club of lipid phases.► Numerous
techniques have elucidated the character traits of bicelles.► Bicelles are exemplary citizens …
techniques have elucidated the character traits of bicelles.► Bicelles are exemplary citizens …
Bicelle samples for solid-state NMR of membrane proteins
AA De Angelis, SJ Opella - Nature protocols, 2007 - nature.com
Magnetically aligned bicelles are an excellent medium for structure determination of
isotopically labeled membrane proteins by solid-state NMR spectroscopy. Bicelles are a …
isotopically labeled membrane proteins by solid-state NMR spectroscopy. Bicelles are a …
[HTML][HTML] Membrane fragmentation by an amyloidogenic fragment of human islet amyloid polypeptide detected by solid-state NMR spectroscopy of membrane …
JR Brender, UHN Dürr, D Heyl, MB Budarapu… - … et Biophysica Acta (BBA …, 2007 - Elsevier
A key factor in the development of Type II diabetes is the loss of insulin producing pancreatic
β-cells. The amyloidogenic human Islet Amyloid Polypeptide (hIAPP also known as human …
β-cells. The amyloidogenic human Islet Amyloid Polypeptide (hIAPP also known as human …
α-Helical transmembrane peptides: a “divide and conquer” approach to membrane proteins
N Bordag, S Keller - Chemistry and physics of lipids, 2010 - Elsevier
α-Helical membrane proteins fulfill many vital roles in all living cells and constitute the
majority of drug targets. However, their relevance is in no way paralleled by our current …
majority of drug targets. However, their relevance is in no way paralleled by our current …
High-resolution NMR spectroscopy of membrane proteins in aligned bicelles
AA De Angelis, AA Nevzorov, SH Park… - Journal of the …, 2004 - ACS Publications
High-resolution solid-state NMR spectra can be obtained from uniformly 15N-labeled
membrane proteins in magnetically aligned bicelles. Fast uniaxial diffusion about the axis of …
membrane proteins in magnetically aligned bicelles. Fast uniaxial diffusion about the axis of …
New gateways to the platinum group metal-catalyzed direct deuterium-labeling method utilizing hydrogen as a catalyst activator
Deuterium-labeled compounds are widely utilized in various scientific fields. We summarize
the recent advances in the direct deuteration of sugar, saturated fatty acid, and arene …
the recent advances in the direct deuteration of sugar, saturated fatty acid, and arene …
Novel lipid system forming hollow microtubes at high yields and concentration
JP Douliez, C Gaillard, L Navailles, F Nallet - Langmuir, 2006 - ACS Publications
There is considerable interest in constructing supramolecular hollow tube architectures
based on amphiphilic molecules. This can be achieved by using relatively expensive …
based on amphiphilic molecules. This can be achieved by using relatively expensive …
Oligomeric structure, dynamics, and orientation of membrane proteins from solid-state NMR
M Hong - Structure, 2006 - cell.com
Solid-state NMR is a versatile and powerful tool for determining the dynamic structure of
membrane proteins at atomic resolution. I review the recent progress in determining the …
membrane proteins at atomic resolution. I review the recent progress in determining the …