Antioxidant Activity, Molecular Docking and Quantum Studies of New Bis‐Schiff Bases Based on Benzyl Phenyl Ketone Moiety

R Ahmad, A Alam, M Khan, T Ali, AA Elhenawy… - …, 2023 - Wiley Online Library
In the current research work novel bis‐Schiff base products of benzyl phenyl ketone nucleus
were synthesized via two step reactions in excellent yields. Using FTIR, EI‐MS and 1H‐NMR …

[HTML][HTML] Synthesis, in vitro, and in silico study of novel pyridine based 1, 3-diphenylurea derivatives as tyrosinase inhibitors

AR Pasha, M Khan, A Khan, J Hussain… - Bioorganic …, 2024 - Elsevier
Tyrosinase inhibitors are studied in the cosmetics and pharmaceutical sectors as tyrosinase
enzyme is involved in the biosynthesis and regulation of melanin, hence these inhibitors are …

Combined experimental and theoretical analyses on design, synthesis, characterization, and in vitro cytotoxic activity evaluation of some novel imino derivatives …

E Başaran, R Çakmak, S Akkoc, S Kaya - Journal of Molecular Structure, 2022 - Elsevier
In this research, some novel Schiff base derivatives 10–18 were synthesized for the first
time, characterized, and tested for their anticancer activities. Spectroscopic characterization …

Schiff base derivatives based on ampyrone as promising acetylcholinesterase inhibitors: Synthesis, spectral characterization, biological activity, and SwissADME …

E Başaran - Russian Journal of Bioorganic Chemistry, 2023 - Springer
In this research, a series of ampyrone-based Schiff base derivatives bearing the biologically
active an aryl sulfonate moiety (X–XVIII) were successfully synthesized and screened for …

Anticholinesterase and antioxidant activities of novel heterocyclic Schiff base derivatives containing an aryl sulfonate moiety

A Kamalı, R Çakmak, M Boğa - Journal of the Chinese …, 2022 - Wiley Online Library
In this research, nine novel heterocyclic Schiff base derivatives (10–18) bearing an aryl
sulfonate moiety were designed, synthesized for the first time, and characterized. Then, their …

Pyrazolone-type compounds (part II): in vitro and in silico evaluation of antioxidant potential; structure–activity relationship

J Branković, VM Milovanović, ZD Petrović… - RSC …, 2023 - pubs.rsc.org
The pyrazolone class comprises a variety of hybrid compounds displaying diverse biological
actions. Although studied for decades, these compounds are still of interest due to their …

Design, docking, synthesis and biological evaluation of novel nicotinohydrazone derivatives as potential butyrylcholinesterase enzyme inhibitor

Yİ Esmer, E Çınar, E Başaran - ChemistrySelect, 2022 - Wiley Online Library
In this research, some new heterocyclic hydrazone compounds bearing an aryl sulfonate
moiety (2 a–i) were facilely synthesized for the first time and elucidated by some …

Synthesis, Characterization, Photoluminescence Properties and Antiproliferative Activity of New Pd (II), Ni (II) and Cu (II) Mixed Complexes Bearing Schiff Base Ligand …

HG Sogukomerogullari, E Başaran… - …, 2023 - Wiley Online Library
In this study, new mixed ligand Cu (II), Ni (II) and Pd (II) metal complexes were synthesized
and characterized by NMR (for ligand), UV‐Vis, elemental analysis, FT‐IR, molar …

Pyrazolone-Based Zn (II) Complexes Display Antitumor Effects in Mutant p53-Carrying Cancer Cells

S Xhafa, C Di Nicola, A Tombesi… - Journal of Medicinal …, 2024 - ACS Publications
The synthesis and characterization of nine Schiff bases of pyrazolone ligands HL n (n= 1–9)
and the corresponding zinc (II) complexes 1–9 of composition [Zn (L n) 2](n= 1–9) are …

Synthesis, antioxidant, and anticholinesterase activities of novel N‐arylsulfonyl hydrazones bearing sulfonate ester scaffold

E Başaran - Journal of the Chinese Chemical Society, 2023 - Wiley Online Library
In this research, two new series of N‐arylsulfonyl hydrazone compounds (14–25)
possessing a sulfonate moiety were synthesized and characterized by elemental analysis …