Integration of optogenetics with complementary methodologies in systems neuroscience

CK Kim, A Adhikari, K Deisseroth - Nature Reviews Neuroscience, 2017 - nature.com
Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …

Septo–hippocampal interaction

C Müller, S Remy - Cell and tissue research, 2018 - Springer
The septo–hippocampal pathway adjusts CA1 network excitability to different behavioral
states and is crucially involved in theta rhythmogenesis. In the medial septum, cholinergic …

Theta oscillations regulate the speed of locomotion via a hippocampus to lateral septum pathway

F Bender, M Gorbati, MC Cadavieco… - Nature …, 2015 - nature.com
Hippocampal theta oscillations support encoding of an animal's position during spatial
navigation, yet longstanding questions about their impact on locomotion remain …

Reconciling the different faces of hippocampal theta: The role of theta oscillations in cognitive, emotional and innate behaviors

T Korotkova, A Ponomarenko, CK Monaghan… - Neuroscience & …, 2018 - Elsevier
Abstract The theta oscillation (5–10 Hz) is a prominent behavior-specific brain rhythm. This
review summarizes studies showing the multifaceted role of theta rhythm in cognitive …

The medial septum controls hippocampal supra-theta oscillations

B Király, A Domonkos, M Jelitai… - nature …, 2023 - nature.com
Hippocampal theta oscillations orchestrate faster beta-to-gamma oscillations facilitating the
segmentation of neural representations during navigation and episodic memory. Supra …

Frequency-selective control of cortical and subcortical networks by central thalamus

J Liu, HJ Lee, AJ Weitz, Z Fang, P Lin, MK Choy… - elife, 2015 - elifesciences.org
Central thalamus plays a critical role in forebrain arousal and organized behavior. However,
network-level mechanisms that link its activity to brain state remain enigmatic. Here, we …

Somatostatin-positive interneurons in the dentate gyrus of mice provide local-and long-range septal synaptic inhibition

M Yuan, T Meyer, C Benkowitz, S Savanthrapadian… - Elife, 2017 - elifesciences.org
Somatostatin-expressing-interneurons (SOMIs) in the dentate gyrus (DG) control formation
of granule cell (GC) assemblies during memory acquisition. Hilar-perforant-path-associated …

Septohippocampal neuromodulation improves cognition after traumatic brain injury

DJ Lee, GG Gurkoff, A Izadi, SE Seidl… - Journal of …, 2015 - liebertpub.com
Traumatic brain injury (TBI) often results in persistent attention and memory deficits that are
associated with hippocampal dysfunction. Although deep brain stimulation (DBS) is used to …

The spatiotemporal organization of experience dictates hippocampal involvement in primary visual cortical plasticity

PSB Finnie, RW Komorowski, MF Bear - Current Biology, 2021 - cell.com
The hippocampus and neocortex are theorized to be crucial partners in the formation of long-
term memories. Here, we assess hippocampal involvement in two related forms of …

Serotonin increases synaptic activity in olfactory bulb glomeruli

J Brill, Z Shao, AC Puche… - Journal of …, 2016 - journals.physiology.org
Serotoninergic fibers densely innervate olfactory bulb glomeruli, the first sites of synaptic
integration in the olfactory system. Acting through 5HT2A receptors, serotonin (5HT) directly …