The blood‐brain barrier (BBB) is a semipermeable and extremely selective system in the
central nervous system of most vertebrates, that separates blood from the brain's …

Blood-brain barrier disruption plays an important role in central nervous system diseases.
This review provides information on the role of mitochondrial oxidative stress in brain …

Microvessels of the blood-brain barrier (BBB) regulate transport into the brain. The highly
specialized brain microvascular endothelial cells, a major component of the BBB, express …

Within the substantially different time scales characterizing human and rodent brain
development, key developmental processes are remarkably preserved. Shared processes …

Microglia, a resident CNS macrophage, are dynamic cells, constantly extending and
retracting their processes as they contact and functionally regulate neurons and other glial …

The construction of the blood–brain barrier (BBB), which is a natural barrier for maintaining
brain homeostasis, is the result of a meticulous organisation in space and time of cell–cell …

The association between maternal immune activation (MIA) during pregnancy and risk for
offspring neuropsychiatric disorders has been increasingly recognized over the past several …

A key element of risk assessment is accounting for the full range of variability in response to
environmental exposures. Default dose-response methods typically assume a 10-fold …

Neonatal hypoxia-ischemia and resulting encephalopathies are of significant concern.
Intrapartum asphyxia is a leading cause of neonatal death globally. Among surviving infants …

Per-and polyfluoroalkyl substances (PFAS) are a class of chemicals that were widely used in
manufacturing and are now present in the environment throughout the world. It is known that …