Desymmetrization of a symmetric skeleton enables late-stage functionalization of molecules.
However, reagent-controlled desymmetrization by site-selective reactions of symmetric …

The addition of two unsymmetric malonate esters to the Buckminster fullerene C60 can lead
to 22 spectroscopically distinguishable isomeric products and therefore represents a …

Abstract Tiara [5] arenes (T [5] s), a new class of five‐fold symmetric oligophenolic
macrocycles that are not accessible from the addition of formaldehyde to phenol, were …

Calixarenes are widely used as molecular platforms in supramolecular chemistry. Their
efficient modification is key for appending functional moieties such as binding, sensing …

Alkenylbenzene skeletons represent one of the most widely occurring structural motifs in
pharmaceutical drugs, natural products, and advanced materials. The construction of …

Iteroselectivity is the selectivity that governs the number of repeating chemical
transformations that occur on a substrate bearing multiple identical reactive functions or …

The selective demethylation of methoxy groups of several multifunctionalized 1, 3, 5-
trimethoxycalix [6] arene-based receptors has been achieved. It is shown in this study that …

We report here on the development of a fluorescent cone homooxacalix [3] arene-based
receptor with a pyrene unit on the wide rim of the macrocycle (Ox3F) for the selective …

A practical four-step synthesis of a model 26-membered N-Boc-protected macrocycle,
starting from commercially available and inexpensive materials, is reported. The crucial …

Rim-differentiated pillar [5] arenes (P [5] s) are intriguing macrocyclic molecular platforms
with C 5-symmetry, but their conventional statistical syntheses suffer from low yields and …