Abnormal regulation and expression of microRNAs (miRNAs) has been documented in
various diseases including cancer. The miRNA let-7 (MIRLET7) family controls …

Breast cancer is a major health problem that affects one in eight women worldwide. As such,
detecting breast cancer at an early stage anticipates better disease outcome and prolonged …

Non-coding RNAs (ncRNAs) have been implicated in most cellular functions. The disruption
of their function through somatic mutations, genomic imprinting, transcriptional and post …

Epigenetic variability (DNA methylation/demethylation, histone modifications, microRNA
regulation) is common in physiological and pathological conditions. Epigenetic alterations …

Innate and acquired chemoresistance exhibited by most tumours exposed to conventional
chemotherapeutic agents account for the majority of relapse cases in cancer patients. Such …

High mobility group AT-hook 2 (HMGA2) is involved in a wide spectrum of biological
processes and is upregulated in several tumors. Here, we collected 273 breast cancer (BC) …

Purpose Accumulating evidence has shown that microRNAs (miRNAs) are promising
biomarkers of neoadjuvant chemotherapy (NAC) response in breast cancer (BC). However …

Of several subtypes of breast cancer, triple negative breast cancer (TNBC) is a highly
aggressive tumor that lacks expression of hormone receptors for estrogen, progesterone …

Awareness of breast cancer has been increasing due to early detection, but the advanced
disease has limited treatment options. There has been growing evidence on the role of …

Due to the positive association between neoadjuvant chemotherapy (NACT) and the
promising early response rates of patients with triple negative breast cancer (TNBC) …