Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man

RJ Fenster, LAM Lebois, KJ Ressler… - Nature Reviews …, 2018 - nature.com
Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly
consequence of exposure to severe psychological trauma. Although effective treatments …

Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective

DW Grupe, JB Nitschke - Nature Reviews Neuroscience, 2013 - nature.com
Uncertainty about a possible future threat disrupts our ability to avoid it or to mitigate its
negative impact and thus results in anxiety. Here, we focus the broad literature on the …

Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study

A Tawakol, A Ishai, RAP Takx, AL Figueroa, A Ali… - The Lancet, 2017 - thelancet.com
Background Emotional stress is associated with increased risk of cardiovascular disease.
We imaged the amygdala, a brain region involved in stress, to determine whether its resting …

[HTML][HTML] Context processing and the neurobiology of post-traumatic stress disorder

I Liberzon, JL Abelson - Neuron, 2016 - cell.com
Progress in clinical and affective neuroscience is redefining psychiatric illness as
symptomatic expression of cellular/molecular dysfunctions in specific brain circuits. Post …

Biological studies of post-traumatic stress disorder

RK Pitman, AM Rasmusson, KC Koenen… - nature Reviews …, 2012 - nature.com
Post-traumatic stress disorder (PTSD) is the only major mental disorder for which a cause is
considered to be known: that is, an event that involves threat to the physical integrity of …

[HTML][HTML] Oxytocin in general anxiety and social fear: a translational approach

ID Neumann, DA Slattery - Biological psychiatry, 2016 - Elsevier
The neuropeptide oxytocin (OXT) has been revealed as a profound anxiolytic and antistress
factor of the brain, besides its many prosocial and reproductive effects. Therefore, there is …

[HTML][HTML] Neural correlates of emotion-attention interactions: From perception, learning, and memory to social cognition, individual differences, and training …

F Dolcos, Y Katsumi, M Moore, N Berggren… - Neuroscience & …, 2020 - Elsevier
Due to their ability to capture attention, emotional stimuli tend to benefit from enhanced
perceptual processing, which can be helpful when such stimuli are task-relevant but …

From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders

MB VanElzakker, MK Dahlgren, FC Davis… - Neurobiology of learning …, 2014 - Elsevier
Abstract Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a
neutral cue to predict a biologically relevant event: after repeated predictive pairings …

Post-traumatic stress disorder: the neurobiological impact of psychological trauma

JE Sherin, CB Nemeroff - Dialogues in clinical neuroscience, 2011 - Taylor & Francis
The classic fight-or-flight response to perceived threat is a reflexive nervous phenomenon
thai has obvious survival advantages in evolutionary terms. However, the systems that …

Effects of yoga on the autonomic nervous system, gamma-aminobutyric-acid, and allostasis in epilepsy, depression, and post-traumatic stress disorder

CC Streeter, PL Gerbarg, RB Saper, DA Ciraulo… - Medical hypotheses, 2012 - Elsevier
A theory is proposed to explain the benefits of yoga practices in diverse, frequently comorbid
medical conditions based on the concept that yoga practices reduce allostatic load in stress …