Cadmium (Cd) is one of the most toxic metals without biological function, and its
accumulation in living organisms has been reported. The kidney is a target organ in Cd …

Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI). The kidney
is susceptible to IRI under several clinical conditions, including hypotension, sepsis, and …

Acute kidney injury is a common clinical disorder and one of the major causes of morbidity
and mortality in the postoperative period. In this study, the safety and efficacy of autologous …

Background Mitochondria are essential organelles that provide energy for cellular functions,
participate in cellular signaling and growth, and facilitate cell death. Based on their …

Abstract Background Mitochondrial transplantation (MTx) is an emerging but poorly
understood technology with the potential to mitigate severe ischemia–reperfusion injuries …

Mitochondrial transplantation involves the replacement or augmentation of native
mitochondria damaged, by ischemia, with viable, respiration-competent mitochondria …

Objectives: To test whether mitochondrial transplantation (MITO) mitigates damage in 2
models of acute kidney injury (AKI). Background: MITO is a process where exogenous …

Acute kidney injury (AKI) is a common clinical disorder associated with decline in renal
function because of ischemic and nephrotoxic insults. The pathophysiology of AKI involves …

Mitochondria, known as the powerhouse of the cell, are at the center of healthy physiology
and provide cells with energy in the form of ATP. These unique organelles are also …

With advancing age, the skeletal muscle phenotype is characterized by a progressive loss of
mass, strength, and quality. This phenomenon, known as sarcopenia, has a negative impact …