[HTML][HTML] Antidiabetic potential of medicinal plants and their active components

B Salehi, A Ata, N V. Anil Kumar, F Sharopov… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus is one of the major health problems in the world, the incidence and
associated mortality are increasing. Inadequate regulation of the blood sugar imposes …

A review on prevention of glycation of proteins: Potential therapeutic substances to mitigate the severity of diabetes complications

S Sarmah, AS Roy - International Journal of Biological Macromolecules, 2022 - Elsevier
Non-enzymatic reaction involving carbonyl of reducing sugars and amino groups in proteins
produces advanced glycation end products (AGEs). AGE accumulation in vivo is a crucial …

The multifunctional roles of flavonoids against the formation of advanced glycation end products (AGEs) and AGEs-induced harmful effects

Q Zhou, KW Cheng, J Xiao, M Wang - Trends in Food Science & …, 2020 - Elsevier
Background Advanced glycation end products (AGEs) play a crucial role in the onset,
progression, and propagation of both macroangiopathy and microangiopathy complications …

[HTML][HTML] A pharmacological appraisal of medicinal plants with antidiabetic potential

V Khan, AK Najmi, M Akhtar, M Aqil… - Journal of Pharmacy …, 2012 - journals.lww.com
Diabetes mellitus is a complicated metabolic disorder that has gravely troubled the human
health and quality of life. Conventional agents are being used to control diabetes along with …

Recent developments in qualitative and quantitative analysis of phytochemical constituents and their metabolites using liquid chromatography–mass spectrometry

H Wu, J Guo, S Chen, X Liu, Y Zhou, X Zhang… - … of pharmaceutical and …, 2013 - Elsevier
Over the past few years, the applications of liquid chromatography coupled with mass
spectrometry (LC–MS) in natural product analysis have been dramatically growing because …

[HTML][HTML] Select polyphenol-rich berry consumption to defer or deter diabetes and diabetes-related complications

A Hameed, M Galli, E Adamska-Patruno, A Krętowski… - Nutrients, 2020 - mdpi.com
Berries are considered “promising functional fruits” due to their distinct and ubiquitous
therapeutic contents of anthocyanins, proanthocyanidins, phenolic acids, flavonoids …

Carboxymethyl-lysine: thirty years of investigation in the field of AGE formation

C Delgado-Andrade - Food & function, 2016 - pubs.rsc.org
In 1985 carboxymethyl-lysine (CML), the first glycoxidation product, was discovered by Dr
Ahmed while trying to identify the major products formed in reactions of glucose with lysine …

Mulberry anthocyanins exert anti-AGEs effects by selectively trapping glyoxal and structural-dependently blocking the lysyl residues of β-lactoglobulins

I Khalifa, D Xia, K Dutta, J Peng, Y Jia, C Li - Bioorganic chemistry, 2020 - Elsevier
Advanced glycation end-products (AGEs), which instigate many disorders, are mostly
mediated by dicarbonyl rearrangements. We studied the corresponding mechanisms of the …

Structures required of polyphenols for inhibiting advanced glycation end products formation

Y Xie, X Chen - Current drug metabolism, 2013 - ingentaconnect.com
The properties of polyphenols as AGEs formation inhibitors have attracted great interest
among researchers. This review discusses the antiglycation activities of polyphenols and …

Inhibition of advanced glycation end product formation by medicinal plant extracts correlates with phenolic metabolites and antioxidant activity

CS Harris, LP Beaulieu, MH Fraser, KL McIntyre… - Planta …, 2011 - thieme-connect.com
Nonenzymatic formation of advanced glycation end products (AGEs) is accelerated under
hyperglycemic conditions characteristic of type 2 diabetes mellitus and contributes to the …