Personalized medicine is probably the most promising area being developed in modern
medicine. This approach attempts to optimize the therapies and the patient care based on …

While global metabolic profiling (untargeted metabolomics) has been the center of much
interest and research activity in the past few decades, more recently targeted metabolomics …

There is a lack of early specific diagnosis and effective evaluation of sepsis, and the clinical
treatment is not timely. As a result, the mortality is high, which seriously threatens the health …

Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis (NS).
Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and …

Antecedentes La infección de aparición tardía es la complicación grave más frecuente
asociada con la atención hospitalaria de los recién nacidos. Debido a que la confirmación …

In the last years,'omics' technologies, and especially metabolomics, emerged as expanding
scientific disciplines and promising technologies in the characterization of several …

Current infection biomarkers are highly limited since they have low capability to predict
infection in the presence of confounding processes such as in non-infectious inflammatory …

Background Early diagnosis of neonatal sepsis is essential to prevent severe complications
and avoid unnecessary use of antibiotics. The mortality of neonatal sepsis is over 18% in …

Given that neonatal sepsis remains an important factor contributing to mortality and
morbidity in neonates, identification of accurate biomarkers to aid in its timely and accurate …

The first days of postnatal life are energetically demanding as metabolic functions change
dramatically to accommodate drastic environmental and physiologic transitions after birth. It …