Nuclear magnetic resonance spectroscopy in clinical metabolomics and personalized medicine: current challenges and perspectives
MPM Letertre, P Giraudeau, P De Tullio - Frontiers in Molecular …, 2021 - frontiersin.org
Personalized medicine is probably the most promising area being developed in modern
medicine. This approach attempts to optimize the therapies and the patient care based on …
medicine. This approach attempts to optimize the therapies and the patient care based on …
Hyphenated MS-based targeted approaches in metabolomics
While global metabolic profiling (untargeted metabolomics) has been the center of much
interest and research activity in the past few decades, more recently targeted metabolomics …
interest and research activity in the past few decades, more recently targeted metabolomics …
A new effective machine learning framework for sepsis diagnosis
There is a lack of early specific diagnosis and effective evaluation of sepsis, and the clinical
treatment is not timely. As a result, the mortality is high, which seriously threatens the health …
treatment is not timely. As a result, the mortality is high, which seriously threatens the health …
New diagnostic possibilities for neonatal sepsis
C Tzialla, P Manzoni, C Achille, L Bollani… - American journal of …, 2018 - thieme-connect.com
Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis (NS).
Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and …
Although diagnosis of sepsis continues to rely on blood culture, this method is too slow and …
C‐reactive protein for diagnosing late‐onset infection in newborn infants
Antecedentes La infección de aparición tardía es la complicación grave más frecuente
asociada con la atención hospitalaria de los recién nacidos. Debido a que la confirmación …
asociada con la atención hospitalaria de los recién nacidos. Debido a que la confirmación …
How could metabolomics change pediatric health?
F Bardanzellu, V Fanos - Italian Journal of Pediatrics, 2020 - Springer
In the last years,'omics' technologies, and especially metabolomics, emerged as expanding
scientific disciplines and promising technologies in the characterization of several …
scientific disciplines and promising technologies in the characterization of several …
Infection biomarkers based on metabolomics
R Araújo, LFN Bento, TAH Fonseca, CP Von Rekowski… - Metabolites, 2022 - mdpi.com
Current infection biomarkers are highly limited since they have low capability to predict
infection in the presence of confounding processes such as in non-infectious inflammatory …
infection in the presence of confounding processes such as in non-infectious inflammatory …
Predictive model for bacterial late-onset neonatal sepsis in a tertiary care hospital in Thailand
D Husada, P Chanthavanich, U Chotigeat… - BMC infectious …, 2020 - Springer
Background Early diagnosis of neonatal sepsis is essential to prevent severe complications
and avoid unnecessary use of antibiotics. The mortality of neonatal sepsis is over 18% in …
and avoid unnecessary use of antibiotics. The mortality of neonatal sepsis is over 18% in …
Neonatal sepsis biomarkers: where are we now?
M Gilfillan, V Bhandari - Research and Reports in Neonatology, 2019 - Taylor & Francis
Given that neonatal sepsis remains an important factor contributing to mortality and
morbidity in neonates, identification of accurate biomarkers to aid in its timely and accurate …
morbidity in neonates, identification of accurate biomarkers to aid in its timely and accurate …
Immunometabolic approaches to prevent, detect, and treat neonatal sepsis
The first days of postnatal life are energetically demanding as metabolic functions change
dramatically to accommodate drastic environmental and physiologic transitions after birth. It …
dramatically to accommodate drastic environmental and physiologic transitions after birth. It …