[HTML][HTML] Metabolic regulatory crosstalk between tumor microenvironment and tumor-associated macrophages

D Chen, X Zhang, Z Li, B Zhu - Theranostics, 2021 - ncbi.nlm.nih.gov
Macrophages phagocytize pathogens to initiate innate immunity and products from the
tumor microenvironment (TME) to mediate tumor immunity. The loss of tumor-associated …

Adiponectin: Structure, physiological functions, role in diseases, and effects of nutrition

K Khoramipour, K Chamari, AA Hekmatikar, A Ziyaiyan… - Nutrients, 2021 - mdpi.com
Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …

Organic NIR-II molecule with long blood half-life for in vivo dynamic vascular imaging

B Li, M Zhao, L Feng, C Dou, S Ding, G Zhou… - Nature …, 2020 - nature.com
Real-time monitoring of vessel dysfunction is of great significance in preclinical research.
Optical bioimaging in the second near-infrared (NIR-II) window provides advantages …

Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease

JJ Fuster, N Ouchi, N Gokce, K Walsh - Circulation research, 2016 - Am Heart Assoc
Obesity is causally linked with the development of cardiovascular disorders. Accumulating
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …

Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue

SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Adiponectin-resistance in obesity

A Engin - Obesity and lipotoxicity, 2017 - Springer
The decrease in adiponectin levels are negatively correlated with chronic subclinical
inflammation markers in obesity. The hypertrophic adipocytes cause obesity-linked insulin …

[HTML][HTML] Adiponectin and metabolic cardiovascular diseases: Therapeutic opportunities and challenges

X Lei, S Qiu, G Yang, Q Wu - Genes & Diseases, 2023 - Elsevier
Metabolic cardiovascular diseases have become a global health concern, and some of their
risk factors are linked to several metabolic disorders. They are the leading causes of death …

C1q/tumor necrosis factor-related protein 9 protects against acute myocardial injury through an adiponectin receptor I-AMPK-dependent mechanism

T Kambara, R Shibata, K Ohashi, K Matsuo… - … and Cellular Biology, 2015 - Taylor & Francis
Obesity is a risk factor for cardiovascular disease. C1q/tumor necrosis factor-related protein
9 (CTRP9) is an adipokine that is downregulated by obesity. We investigated the role of …

Between inflammation and autophagy: the role of leptin-adiponectin axis in cardiac remodeling

L Kamareddine, CM Ghantous, S Allouch… - Journal of …, 2021 - Taylor & Francis
Cardiac remodeling is the process by which the heart adapts to stressful stimuli, such as
hypertension and ischemia/reperfusion; it ultimately leads to heart failure upon long-term …

Large reduction in adiponectin during pregnancy is associated with large-for-gestational-age newborns

T Lekva, MCP Roland, AE Michelsen… - The Journal of …, 2017 - academic.oup.com
Context: Fetuses exposed to an obese intrauterine environment are more likely to be born
large-for-gestational age (LGA) and are at increased risk of obesity in childhood and …