Novel CRISPR–Cas systems: an updated review of the current achievements, applications, and future research perspectives
According to Darwin's theory, endless evolution leads to a revolution. One such example is
the Clustered Regularly Interspaced Palindromic Repeats (CRISPR)–Cas system, an …
the Clustered Regularly Interspaced Palindromic Repeats (CRISPR)–Cas system, an …
The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …
DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
during the reoxygenation phase following hypoxia, is well known in a variety of acute …
Dysbiosis of Gut Microbiota from the Perspective of the Gut–Brain Axis: Role in the Provocation of Neurological Disorders
The gut–brain axis is a bidirectional communication network connecting the gastrointestinal
tract and central nervous system. The axis keeps track of gastrointestinal activities and …
tract and central nervous system. The axis keeps track of gastrointestinal activities and …
Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines
Background Humoral immune responses to infectious agents or vaccination vary
substantially among individuals, and many of the factors responsible for this variability …
substantially among individuals, and many of the factors responsible for this variability …
Unraveling the viral dark matter through viral metagenomics
TM Santiago-Rodriguez, EB Hollister - Frontiers in immunology, 2022 - frontiersin.org
Viruses are part of the microbiome and have essential roles in immunology, evolution,
biogeochemical cycles, health, and disease progression. Viruses influence a wide variety of …
biogeochemical cycles, health, and disease progression. Viruses influence a wide variety of …
Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells
Viruses causing chronic infection artfully manipulate infected cells to enable viral
persistence in vivo under the pressure of immunity. Human T-cell leukemia virus type 1 …
persistence in vivo under the pressure of immunity. Human T-cell leukemia virus type 1 …
Direct antiviral mechanisms of interferon-gamma
Interferon-gamma (IFNG) is a pleiotropic cytokine that modulates both innate and adaptive
immune networks; it is the most potent activator of macrophages and a signature cytokine of …
immune networks; it is the most potent activator of macrophages and a signature cytokine of …
[HTML][HTML] Therapeutic potentials of CRISPR-Cas genome editing technology in human viral infections
Viral infections are a common cause of morbidity worldwide. The emergence of Coronavirus
Disease 2019 (COVID-19) has led to more attention to viral infections and finding novel …
Disease 2019 (COVID-19) has led to more attention to viral infections and finding novel …
Association between viral infections and risk of autistic disorder: an overview
Autism spectrum disorder (ASD) is a neurodevelopmental condition of the central nervous
system (CNS) that presents with severe communication problems, impairment of social …
system (CNS) that presents with severe communication problems, impairment of social …
[HTML][HTML] Common viral infections in kidney transplant recipients
J Vanichanan, S Udomkarnjananun… - Kidney research and …, 2018 - ncbi.nlm.nih.gov
Infectious complications have been considered as a major cause of morbidity and mortality
after kidney transplantation, especially in the Asian population. Therefore, prevention, early …
after kidney transplantation, especially in the Asian population. Therefore, prevention, early …