Targeting Nrf2 signaling pathway and oxidative stress by resveratrol for Parkinson's disease: an overview and update on new developments
Parkinson's disease (PD) as a prevalent neurodegenerative condition impairs motor function
and is caused by the progressive deterioration of nigrostriatal dopaminergic (DAergic) …
and is caused by the progressive deterioration of nigrostriatal dopaminergic (DAergic) …
Ferritinophagy and α-Synuclein: pharmacological targeting of autophagy to restore iron regulation in Parkinson's disease
MK Boag, A Roberts, VN Uversky, L Ma… - International journal of …, 2022 - mdpi.com
A major hallmark of Parkinson's disease (PD) is the fatal destruction of dopaminergic
neurons within the substantia nigra pars compacta. This event is preceded by the formation …
neurons within the substantia nigra pars compacta. This event is preceded by the formation …
In vitro modelling of Parkinson's disease using 6-OHDA is associated with increased NQO2 activity
ER Verbovaya, IA Kadnikov, IO Logvinov, TA Antipova… - Toxicology in Vitro, 2024 - Elsevier
The pathogenesis of Parkinson's disease (PD) involves abnormalities in the metabolism of
catecholamines. The enzyme quinone reductase 2 (NQO2) reduces quinone derivatives of …
catecholamines. The enzyme quinone reductase 2 (NQO2) reduces quinone derivatives of …
The role of voltage-gated calcium channels in the pathogenesis of Parkinson's disease
A Sandoval, P Duran, A Corzo-López… - International Journal …, 2024 - Taylor & Francis
Abstract Aim: Voltage-gated calcium (CaV) channels play an essential role in maintaining
calcium homeostasis and regulating numerous physiological processes in neurons …
calcium homeostasis and regulating numerous physiological processes in neurons …
[HTML][HTML] Suppressing ERp57 diminishes osteoclast activity and ameliorates ovariectomy-induced bone loss via the intervention in calcium oscillation and the …
T Yuan, Y Wang, H Wang, Q Lu, X Zhang, Z Li, S Sun - Heliyon, 2024 - cell.com
Background Increased osteoclast activity constitutes the primary etiology of excessive bone
erosion in postmenopausal osteoporosis. ERp57, otherwise referred to as protein disulfide …
erosion in postmenopausal osteoporosis. ERp57, otherwise referred to as protein disulfide …
[HTML][HTML] The role of iron transporters and regulators in Alzheimer's disease and Parkinson's disease: Pathophysiological insights and therapeutic prospects
S Tian, B Wang, Y Ding, Y Zhang, P Yu… - Biomedicine & …, 2024 - Elsevier
Brain iron homeostasis plays a vital role in maintaining brain development and controlling
neuronal function under physiological conditions. Many studies have shown that the …
neuronal function under physiological conditions. Many studies have shown that the …
Coupled effects of channels and synaptic dynamics in stochastic modelling of healthy and Parkinson's-disease-affected brains
Our brain is a complex information processing network in which the nervous system receives
information from the environment to quickly react to incoming events or learns from …
information from the environment to quickly react to incoming events or learns from …
[引用][C] Unraveling the Role of Cyanidin-3-Glucoside as Calcium Channels Blocker: Therapeutic Advancement for Parkinson Disease Shaheen Kousar, 2Dr. Shazia …
S Kousar