Emerging therapies for glioblastoma: current state and future directions

L Rong, N Li, Z Zhang - Journal of Experimental & Clinical Cancer …, 2022 - Springer
Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor with an
extremely poor prognosis. Given the poor survival with currently approved treatments for …

Self-assembled peptide and protein nanostructures for anti-cancer therapy: Targeted delivery, stimuli-responsive devices and immunotherapy

M Delfi, R Sartorius, M Ashrafizadeh, E Sharifi, Y Zhang… - Nano Today, 2021 - Elsevier
Self-assembled peptides and proteins possess tremendous potential as targeted drug
delivery systems and key applications of these well-defined nanostructures reside in anti …

Oxidative stress in autism spectrum disorder—current progress of mechanisms and biomarkers

X Liu, J Lin, H Zhang, NU Khan, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a type of neurodevelopmental disorder that has been
diagnosed in an increasing number of children around the world. Existing data suggest that …

[HTML][HTML] The many faces of cobalamin (vitamin B12) deficiency

BHR Wolffenbuttel, HJCM Wouters… - Mayo clinic proceedings …, 2019 - Elsevier
Although cobalamin (vitamin B 12) deficiency was described over a century ago, it is still
difficult to establish the correct diagnosis and prescribe the right treatment. Symptoms …

Vitamin B12 status in health and disease: a critical review. Diagnosis of deficiency and insufficiency – clinical and laboratory pitfalls

A Sobczyńska-Malefora, E Delvin… - Critical reviews in …, 2021 - Taylor & Francis
Vitamin B12 (cobalamin) is an essential cofactor for two metabolic pathways. It is obtained
principally from food of animal origin. Cobalamin becomes bioavailable through a series of …

[HTML][HTML] Happily (n) ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

A Höhn, D Weber, T Jung, C Ott, M Hugo, B Kochlik… - Redox biology, 2017 - Elsevier
Aging is a complex phenomenon and its impact is becoming more relevant due to the rising
life expectancy and because aging itself is the basis for the development of age-related …

Understanding the role of the gut microbiome in brain development and its association with neurodevelopmental psychiatric disorders

S Dash, YA Syed, MR Khan - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …

The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders

R Fetit, RF Hillary, DJ Price, SM Lawrie - Neuroscience & Biobehavioral …, 2021 - Elsevier
Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …

Vitamin B12 deficiency

R Green, LH Allen, AL Bjørke-Monsen, A Brito… - Nature reviews Disease …, 2017 - nature.com
Abstract Vitamin B 12 (B12; also known as cobalamin) is a B vitamin that has an important
role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial …

Maternal Multivitamin Intake, Plasma Folate and Vitamin B12 Levels and Autism Spectrum Disorder Risk in Offspring

R Raghavan, AW Riley, H Volk… - Paediatric and …, 2018 - Wiley Online Library
Background To examine the prospective association between multivitamin supplementation
during pregnancy and biomarker measures of maternal plasma folate and vitamin B12 …