Photochemical approaches to complex chemotypes: applications in natural product synthesis
The use of photochemical transformations is a powerful strategy that allows for the formation
of a high degree of molecular complexity from relatively simple building blocks in a single …
of a high degree of molecular complexity from relatively simple building blocks in a single …
Recent advances in the synthesis of cyclobutanes by olefin [2+ 2] photocycloaddition reactions
S Poplata, A Tröster, YQ Zou, T Bach - Chemical Reviews, 2016 - ACS Publications
The [2+ 2] photocycloaddition is undisputedly the most important and most frequently used
photochemical reaction. In this review, it is attempted to cover all recent aspects of [2+ 2] …
photochemical reaction. In this review, it is attempted to cover all recent aspects of [2+ 2] …
Strategic application of C–H oxidation in natural product total synthesis
The oxidation of unactivated C–H bonds has emerged as an effective tactic in natural
product synthesis and has altered how chemists approach the synthesis of complex …
product synthesis and has altered how chemists approach the synthesis of complex …
Oxetanes: recent advances in synthesis, reactivity, and medicinal chemistry
JA Bull, RA Croft, OA Davis, R Doran… - Chemical …, 2016 - ACS Publications
The four-membered oxetane ring has been increasingly exploited for its contrasting
behaviors: its influence on physicochemical properties as a stable motif in medicinal …
behaviors: its influence on physicochemical properties as a stable motif in medicinal …
Photochemical reactions as key steps in natural product synthesis
T Bach, JP Hehn - Angewandte Chemie International Edition, 2011 - Wiley Online Library
Photochemical reactions contribute in a significant way to the existing repertoire of carbon–
carbon bond‐forming reactions by allowing access to exceptional molecular structures that …
carbon bond‐forming reactions by allowing access to exceptional molecular structures that …
Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis
R Long, J Huang, J Gong, Z Yang - Natural Product Reports, 2015 - pubs.rsc.org
Covering: 2000 to 2015 Molecules containing vicinal all-carbon quaternary stereocenters
are found in many secondary metabolites, and they exhibit a variety of biological and …
are found in many secondary metabolites, and they exhibit a variety of biological and …
Terpenoids with special pharmacological significance: A review
R Jaeger, E Cuny - Natural product communications, 2016 - journals.sagepub.com
Terpenoids are a very prominent class of natural compounds produced in diverse genera of
plants, fungi, algae and sponges. They gained significant pharmaceutical value since …
plants, fungi, algae and sponges. They gained significant pharmaceutical value since …
Development of a Terpene Feedstock-Based Oxidative Synthetic Approach to the Illicium Sesquiterpenes
K Hung, ML Condakes, LFT Novaes… - Journal of the …, 2019 - ACS Publications
The Illicium sesquiterpenes are a family of natural products containing over 100 highly
oxidized and structurally complex members, many of which display interesting biological …
oxidized and structurally complex members, many of which display interesting biological …
Neurotrophic natural products: chemistry and biology
J Xu, MH Lacoske… - Angewandte Chemie …, 2014 - Wiley Online Library
Neurodegenerative diseases and spinal cord injury affect approximately 50 million people
worldwide, bringing the total healthcare cost to over 600 billion dollars per year. Nervous …
worldwide, bringing the total healthcare cost to over 600 billion dollars per year. Nervous …
Photochemische Reaktionen als Schlüsselschritte in der Naturstoffsynthese
T Bach, JP Hehn - Angewandte Chemie, 2011 - Wiley Online Library
Photochemische Reaktionen bereichern in signifikanter Weise das Repertoire zur Knüpfung
von Kohlenstoff‐Kohlenstoff‐Bindungen und machen ungewöhnliche, auf herkömmlichem …
von Kohlenstoff‐Kohlenstoff‐Bindungen und machen ungewöhnliche, auf herkömmlichem …