This review article will consider the preparation and application of ynones in synthetic
organic chemistry. Concerning the preparation of these bifunctional compounds, several …

Ynones are widely used in organic synthesis. Their great success is rooted in their multiple
functional groups. This review focus on advance of ynones in published in the decade 2009 …

Indole-ynones have been established as general substrates for radical dearomatizing
spirocyclization cascade reactions. Five distinct and varied synthetic protocols have been …

Indoles are amongst the most important classes of heteroaromatics in organic chemistry,
commonly found in biologically active natural products and therapeutically useful …

An operationally simple, high yielding three-step cascade process is described for the direct
conversion of indole-tethered ynones into functionalized quinolines. A single “multitasking” …

An efficient silver (I)-catalyzed method is reported for the synthesis of substituted indoles,
most notably 5-hydroxy-derivatives, via π-acidic alkyne activation. Most methods for the …

Cascade reactions are green and powerful transformations for building multiple carbon–
carbon bonds in one step. Through a relay olefination and radical addition process, we were …

This review concentrates on our research into the discovery of novel ynone-based
dearomative spirocyclisation processes, whilst placing the new chemistry into the context of …

Indolizidine alkaloids such as anticancer drugs vinblastine and vincristine are exceptionally
attractive due to their widespread occurrence, prominent bioactivity, complex structure, and …

The great success of ynones in synthesis is rooted in their multiple functional groups.
Herein, reactions triggered by the reflex‐Michael addition, ynones in copper (I)‐catalyzed …