Idiopathic REM sleep behaviour disorder and neurodegeneration—an update

B Högl, A Stefani, A Videnovic - Nature Reviews Neurology, 2018 - nature.com
So-called idiopathic rapid eye movement (REM) sleep behaviour disorder (RBD), formerly
seen as a rare parasomnia, is now recognized as the prodromal stage of an α …

The risk of neurodegeneration in REM sleep behavior disorder: a systematic review and meta-analysis of longitudinal studies

A Galbiati, L Verga, E Giora, M Zucconi… - Sleep medicine …, 2019 - Elsevier
Several studies report an association between REM Sleep Behavior Disorder (RBD) and
neurodegenerative diseases, in particular synucleinopathies. Interestingly, the onset of RBD …

Cognitive heterogeneity in Parkinson's disease: A mechanistic view

M Carceles-Cordon, D Weintraub, AS Chen-Plotkin - Neuron, 2023 - cell.com
Cognitive impairment occurs in most individuals with Parkinson's disease (PD), exacting a
high toll on patients, their caregivers, and the healthcare system. In this review, we begin by …

The influence of age and gender on motor and non-motor features of early Parkinson's disease: initial findings from the Oxford Parkinson Disease Center (OPDC) …

K Szewczyk-Krolikowski, P Tomlinson, K Nithi… - Parkinsonism & related …, 2014 - Elsevier
Background Identifying factors influencing phenotypic heterogeneity in Parkinson's Disease
is crucial for understanding variability in disease severity and progression. Age and gender …

Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study

A Iranzo, F Valldeoriola, F Lomeña… - The Lancet …, 2011 - thelancet.com
Background Serial dopamine transporter (DAT) imaging in patients with Parkinson's disease
(PD) and other synucleinopathies shows progressive nigrostriatal dopaminergic dysfunction …

REM sleep behavior disorder: motor manifestations and pathophysiology

I Arnulf - Movement Disorders, 2012 - Wiley Online Library
Patients with REM sleep behavior disorder (RBD) enact violent dreams during REM sleep in
the absence of normal muscle atonia. This disorder is highly frequent in patients with …

The neuropsychiatry of Parkinson disease: a perfect storm

D Weintraub, E Mamikonyan - The American Journal of Geriatric Psychiatry, 2019 - Elsevier
Affective disorders, cognitive decline, and psychosis have long been recognized as common
in Parkinson disease (PD), and other psychiatric disorders include impulse control …

Idiopathic REM sleep behaviour disorder in the development of Parkinson's disease

BF Boeve - The Lancet Neurology, 2013 - thelancet.com
Parkinson's disease is a progressive neurodegenerative disorder associated with Lewy
body disease pathology in central and peripheral nervous system structures. Although the …

[HTML][HTML] Parasomnias: an updated review

MJ Howell - Neurotherapeutics, 2012 - Elsevier
Parasomnias are abnormal behaviors emanating from or associated with sleep.
Sleepwalking and related disorders result from an incomplete dissociation of wakefulness …

Cognitive changes in prodromal Parkinson's disease: a review

S Fengler, I Liepelt‐Scarfone, K Brockmann… - Movement …, 2017 - Wiley Online Library
Although other nonmotor phenomena representing possible prodromal symptoms of
Parkinson's disease have been described in some detail, the occurrence and characteristics …