Antimicrobial photodynamic therapy–what we know and what we don't

F Cieplik, D Deng, W Crielaard… - Critical reviews in …, 2018 - Taylor & Francis
Considering increasing number of pathogens resistant towards commonly used antibiotics
as well as antiseptics, there is a pressing need for antimicrobial approaches that are …

Periodontal diseases

DF Kinane, PG Stathopoulou… - Nature reviews Disease …, 2017 - nature.com
Periodontal diseases comprise a wide range of inflammatory conditions that affect the
supporting structures of the teeth (the gingiva, bone and periodontal ligament), which could …

A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans

N Dutzan, T Kajikawa, L Abusleme… - Science translational …, 2018 - science.org
Periodontitis is one of the most common human inflammatory diseases, yet the mechanisms
that drive immunopathology and could be therapeutically targeted are not well defined …

Antibiotics/antimicrobials: systemic and local administration in the therapy of mild to moderately advanced periodontitis

K Jepsen, S Jepsen - Periodontology 2000, 2016 - Wiley Online Library
This review gives an update of the current scientific evidence on the efficacy of the
adjunctive use of systemic and local antibiotics/antimicrobials in the treatment of …

Application of ligature-induced periodontitis in mice to explore the molecular mechanism of periodontal disease

P Lin, H Niimi, Y Ohsugi, Y Tsuchiya… - International journal of …, 2021 - mdpi.com
Periodontitis is an inflammatory disease characterized by the destruction of the
periodontium. In the last decade, a new murine model of periodontitis has been widely used …

Periodontal diseases

BL Pihlstrom, BS Michalowicz, NW Johnson - The lancet, 2005 - thelancet.com
The periodontal diseases are highly prevalent and can affect up to 90% of the worldwide
population. Gingivitis, the mildest form of periodontal disease, is caused by the bacterial …

Antibiotic resistance in human chronic periodontitis microbiota

TE Rams, JE Degener… - Journal of …, 2014 - Wiley Online Library
Background: Patients with chronic periodontitis (CP) may yield multiple species of putative
periodontal bacterial pathogens that vary in their antibiotic drug susceptibility. This study …

The use and misuse of antibiotics in dentistry: A scoping review

K Stein, J Farmer, S Singhal, F Marra… - The Journal of the …, 2018 - Elsevier
Background To describe antibiotic prescribing behaviors in dentistry, including clinical and
nonclinical indications for their use, the type and regimen of antibiotics prescribed, and …

Antimicrobial therapy in periodontitis: the use of systemic antimicrobials against the subgingival biofilm

D Herrera, B Alonso, R León… - Journal of clinical …, 2008 - Wiley Online Library
Objectives: The aim was to answer three relevant questions: can systemic antimicrobials be
efficacious if the biofilm is not disrupted? Can the type of debridement of the subgingival …

Improved drug loading and antibacterial activity of minocycline-loaded PLGA nanoparticles prepared by solid/oil/water ion pairing method

TSJ Kashi, S Eskandarion… - International journal …, 2012 - Taylor & Francis
Background Low drug entrapment efficiency of hydrophilic drugs into poly (lactic-co-glycolic
acid)(PLGA) nanoparticles is a major drawback. The objective of this work was to investigate …