Compritol 888 ATO: a multifunctional lipid excipient in drug delivery systems and nanopharmaceuticals

MH Aburahma, SM Badr-Eldin - Expert opinion on drug delivery, 2014 - Taylor & Francis
Introduction: Compritol® 888 ATO is a lipid excipient that is generally used in cosmetic
industry as a surfactant, emulsifying agent and viscosity-inducing agent in emulsions or …

Twin-screw extruder in pharmaceutical industry: history, working principle, applications, and marketed products: an in-depth review

M Dhaval, S Sharma, K Dudhat, J Chavda - Journal of Pharmaceutical …, 2022 - Springer
Abstract Twin-screw extruder (TSE), originally built and developed for plastic and rubber
industries approximately 100 years ago, is now slowly but steadily gaining popularity in the …

Twin-screw melt granulation for oral solid pharmaceutical products

SP Forster, E Dippold, T Chiang - Pharmaceutics, 2021 - mdpi.com
This article highlights the advantages of pharmaceutical continuous melt granulation by twin-
screw extrusion. The different melt granulation process options and excipients are described …

Development and characterization of sustained-released donepezil hydrochloride solid dispersions using hot melt extrusion technology

A Alshetaili, BK Almutairy, SM Alshehri, MA Repka - Pharmaceutics, 2021 - mdpi.com
The aim of this work was to develop the sustained release formulation of donepezil
hydrochloride (DH) using the hot-melt extruded solid dispersion technique via the rational …

Preparation of sildenafil citrate microcapsules and in vitro/in vivo evaluation of taste masking efficiency

EJ Yi, JY Kim, YS Rhee, SH Kim, HJ Lee… - International journal of …, 2014 - Elsevier
The aim of the present study was to prepare the particulate taste-masking system to mask
the bitter taste of sildenafil citrate (SC), a well-known phosphodiesterase-5 inhibitor used for …

SEM/EDX and confocal Raman microscopy as complementary tools for the characterization of pharmaceutical tablets

N Scoutaris, K Vithani, I Slipper, B Chowdhry… - International journal of …, 2014 - Elsevier
The drug distribution on the surface of hot-melt extruded, pre-mixed hot-melt extruded and
direct compressed tablet formulations was characterized by using scanning electron …

Preparation, characterization, and in vitro release of microencapsulated essential oil hydroxyapatite pellets filled into multifunctional capsules

I Partheniadis, M Koukourikou, D Tsalavouti… - Journal of Drug Delivery …, 2023 - Elsevier
Oregano essential oil (EO)–loaded pellets were prepared using calcium phosphate
substrates of different specific surface areas (S w) and as binders EO in water emulsions …

Evaluation of carvedilol compatibility with lipid excipients for the development of lipid-based drug delivery systems

LAD Silva, FV Teixeira, RC Serpa, NL Esteves… - Journal of thermal …, 2016 - Springer
Carvedilol (CARV) is a widely used non-selective β-blocker, which has shown low
bioavailability after oral administration (20%) due to its low water solubility and intense first …

[HTML][HTML] Sustained release of 3D printed bupropion hydrochloride tablets bearing Braille imprints for the visually impaired

C Protopapa, A Siamidi, LA Junqueira… - International Journal of …, 2024 - Elsevier
Abstract 3D printing has been introduced as a novel approach for the design of personalized
dosage forms and support patient groups with special needs that require additional …

Twin-screw extrusion of sustained-release oral dosage forms and medical implants

X Feng, F Zhang - Drug delivery and translational research, 2018 - Springer
Most of published reviews of twin-screw extrusion focused on its application for enhancing
the bioavailability of amorphous solid dispersions while few of them focused on its use for …