Point-of-care electrochemical testing of biomarkers involved in inflammatory and inflammatory-associated medical conditions

DG Macovei, MB Irimes, O Hosu, C Cristea… - Analytical and …, 2023 - Springer
Recent years have shown that the diagnosis and monitoring of biomarkers involved in
inflammatory-associated medical conditions such as cancer, neurological disorders, viral …

Development and classification of RNA aptamers for therapeutic purposes: an updated review with emphasis on cancer

M Razlansari, S Jafarinejad, A Rahdar… - Molecular and Cellular …, 2023 - Springer
Today, RNA aptamers are being considered promising theranostic tools against a wide
variety of disorders. RNA aptamers can fold into complex shapes and bind to diverse …

New challenges in point of care electrochemical detection of clinical biomarkers

S Campuzano, M Pedrero, P Yáñez-Sedeño… - Sensors and Actuators B …, 2021 - Elsevier
Point of care testing (POCT), ie, medical tests performed wherever the patient is with the
possibility to immediately get and send the results to the doctor for clinical decision making …

A CdSe@ CdS quantum dots based electrochemiluminescence aptasensor for sensitive detection of ochratoxin A

M Jia, B Jia, X Liao, L Shi, Z Zhang, M Liu, L Zhou, D Li… - Chemosphere, 2022 - Elsevier
In this work, a CdSe@ CdS quantum dots (QDs) based label-free electrochemiluminescence
(ECL) aptasensor was developed for the specific and sensitive detection of ochratoxin A …

New insights in aptamer-targeted nanoliposomes for the treatment of breast cancer

NJ Singhai, R Maheshwari, K Khatri - Journal of Drug Delivery Science and …, 2023 - Elsevier
Despite significant advances in understanding breast cancer pathogenesis and prognosis, it
remains one of the most common causes of death for women worldwide. To develop a more …

A highly sensitive nanobiosensor based on aptamer-conjugated graphene-decorated rhodium nanoparticles for detection of HER2-positive circulating tumor cells

M Sadeghi, S Kashanian, SM Naghib… - Nanotechnology …, 2022 - degruyter.com
Assessment of human epidermal growth factor receptor-2 (HER2) tumor marker status is an
impressive factor in screening, diagnosing and monitoring breast cancer (BC). The …

Screening of a High-Affinity Aptamer for Aflatoxin M1 and Development of Its Colorimetric Aptasensor

X Wei, P Ma, K Imran Mahmood… - Journal of Agricultural …, 2023 - ACS Publications
Aflatoxin M1 (AFM1), a secondary metabolite of Aspergillus spp., is highly toxic and widely
present in food matrices. Therefore, the detection of AFM1 is of great importance for the …

[HTML][HTML] Electrochemical bioanalysis: all that still hides the tip of the iceberg

S Campuzano, JM Pingarrón - Current Opinion in Electrochemistry, 2023 - Elsevier
The tremendous advances in electrochemical biosensing that have occurred recently,
highlighting as never before the versatility and adaptability of the resulting biotools, together …

critical design factors for electrochemical aptasensors based on target-induced conformational changes: The case of small-molecule targets

AM Onaş, C Dascălu, MD Raicopol, L Pilan - Biosensors, 2022 - mdpi.com
Nucleic-acid aptamers consisting in single-stranded DNA oligonucleotides emerged as very
promising biorecognition elements for electrochemical biosensors applied in various fields …

Therapeutic Potential of Aptamer–Protein Interactions

AS Shraim, BA Abdel Majeed… - ACS Pharmacology & …, 2022 - ACS Publications
Aptamers are single-stranded oligonucleotides (RNA or DNA) with a typical length between
25 and 100 nucleotides which fold into three-dimensional structures capable of binding to …