Marine natural products
Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382–431 This review covers the
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …
Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads?
P Sivalingam, K Hong, J Pote… - International Journal of …, 2019 - Wiley Online Library
Antimicrobial resistance (AR) is recognized as one of the greatest threats to public health
and in global concern. Consequently, the increased morbidity and mortality, which are …
and in global concern. Consequently, the increased morbidity and mortality, which are …
Structural diversity, biosynthesis, and biological functions of lipopeptides from Streptomyces
S Zhang, Y Chen, J Zhu, Q Lu, MJ Cryle… - Natural Product …, 2023 - pubs.rsc.org
Covering: up to 2022 Streptomyces are ubiquitous in terrestrial and marine environments,
where they display a fascinating metabolic diversity. As a result, these bacteria are a prolific …
where they display a fascinating metabolic diversity. As a result, these bacteria are a prolific …
Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function
Covering: up to January 2017 Cytochrome P450 enzymes (P450s) are some of the most
exquisite and versatile biocatalysts found in nature. In addition to their well-known roles in …
exquisite and versatile biocatalysts found in nature. In addition to their well-known roles in …
Biosynthetic pathways to nonproteinogenic α-amino acids
JB Hedges, KS Ryan - Chemical reviews, 2019 - ACS Publications
Natural nonproteinogenic amino acids vastly outnumber the well-known 22 proteinogenic
amino acids. Such amino acids are generated in specialized metabolic pathways. In these …
amino acids. Such amino acids are generated in specialized metabolic pathways. In these …
Current status and future prospects of marine natural products (MNPs) as antimicrobials
A Choudhary, LM Naughton, I Montánchez… - Marine drugs, 2017 - mdpi.com
The marine environment is a rich source of chemically diverse, biologically active natural
products, and serves as an invaluable resource in the ongoing search for novel …
products, and serves as an invaluable resource in the ongoing search for novel …
Deep sea actinomycetes and their secondary metabolites
M Kamjam, P Sivalingam, Z Deng, K Hong - Frontiers in Microbiology, 2017 - frontiersin.org
Deep sea is a unique and extreme environment. It is a hot spot for hunting marine
actinomycetes resources and secondary metabolites. The novel deep sea actinomycete …
actinomycetes resources and secondary metabolites. The novel deep sea actinomycete …
Targeted and logical discovery of piperazic acid-bearing natural products based on genomic and spectroscopic signatures
A targeted and logical discovery method was devised for natural products containing
piperazic acid (Piz), which is biosynthesized from ornithine by l-ornithine N-hydroxylase …
piperazic acid (Piz), which is biosynthesized from ornithine by l-ornithine N-hydroxylase …
[PDF][PDF] Natural product reports
JW Blunt, BR Copp, RA Keyzers, MH Munroa… - Nat Prod Rep, 2016 - academia.edu
This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …
1220 citations (792 for the period January to December 2015) referring to compounds …
[HTML][HTML] Complex peptide natural products: biosynthetic principles, challenges and opportunities for pathway engineering
SL Wenski, S Thiengmag, EJN Helfrich - Synthetic and systems …, 2022 - Elsevier
Complex peptide natural products exhibit diverse biological functions and a wide range of
physico-chemical properties. As a result, many peptides have entered the clinics for various …
physico-chemical properties. As a result, many peptides have entered the clinics for various …