The macrophage is a key cell in the pro-and anti-inflammatory response including that of the
inflammatory microenvironment of malignant tumors. Much current drug development in …

Adipose tissue releases bioactive mediators called adipokines. This review focuses on the
effects of omentin, vaspin, cardiotrophin-1, Tumor necrosis factor-like Weak Inducer of …

The haptoglobin‐(Hp‐) CD163‐heme oxygenase‐1 (HO‐1) pathway is an efficient captor‐
receptor‐enzyme system to circumvent the hemoglobin (Hb)/heme‐induced toxicity during …

TWEAK (tumor necrosis factor-like weak inducer of apoptosis) is a member of the TNF
superfamily that controls a multitude of cellular events including proliferation, migration …

Macrophages exert important functions in the balance and efficiency of immune responses,
and participate in innate and adaptive immunity. The proinflammatory actions of …

Ligands and receptors of the tumor necrosis factor (TNF) superfamily regulate immune
responses and homeostatic functions with potential diagnostic and therapeutic implications …

Obesity and type 2 diabetes (T2D) are associated with chronic low-grade inflammation.
Mounting evidence suggests the involvement of an inflammatory switch in adipose tissue …

The present study sought to evaluate the effect of resveratrol supplementation on mRNA
expression levels of peroxisome proliferator‐activated receptor alpha (PPARα), p53, p21 …

The TWEAK/Fn14 pathway is now well-known for its involvement in the modulation of
inflammation in various human autoimmune/chronic inflammatory diseases (AICID) …

Context: Soluble TNF-like weak inducer of apoptosis (sTWEAK) is generated by the
intracellular proteolytic cleavage of full-length membrane-bound TNF-like weak inducer of …