The existing epidemiologic literature was comprehensively reviewed to retrieve all
epidemiologic studies (case control and cohort studies) that examined exposure to …

Chronic inflammation is recognized as a threat factor for cancer progression. Release of
inflammatory molecules generates microenvironment which is highly favorable for …

Cohesive scientific evidence from molecular, animal, and human investigations supports the
hypothesis that aberrant induction of COX-2 and up-regulation of the prostaglandin cascade …

Breast cancer has a high incidence worldwide. The results of substantial studis reveal that
inflammation plays an important role in the initiation, development, and aggressiveness of …

Hepatocellular carcinoma (HCC) is the fifth most common cancer, and hepatitis C virus
(HCV) infection plays a major role in HCC development. The molecular mechanisms by …

Tumor viruses have provided relatively simple genetic systems, which can be manipulated
for understanding the molecular mechanisms of the cellular transformation process. A …

Epstein-Barr virus nuclear antigens EBNA3A EBNA3A, EBNA3B EBNA3B and EBNA3C
EBNA3C are a family of three large latency-associated proteins expressed in B cells …

The NME family of proteins is composed of 10 isoforms, designated NME1-10, which are
diverse in their enzymatic activities and patterns of subcellular localization. Each contains a …

The role of cyclooxygenase-2 (COX-2), its lipid metabolite prostaglandin E2 (PGE2), and
Eicosanoid (EP) receptors (EP; 1-4) underlying the proinflammatory mechanistic aspects of …

Inflammation is a major cause of cancer and may condition its progression. The deregulation
of the cyclooxygenase (COX) pathway is implicated in several pathophysiological …