Purpose As molecules responsible for presenting antigens to T lymphocytes, leukocytes
antigens (HLAs) play a vital role in cancer immunology. This review aims to provide current …

The field of immuno-oncology is now at the forefront of cancer care and is rapidly evolving.
The immune checkpoint blockade has been demonstrated to restore antitumor responses in …

Human papillomavirus (HPV) is recognized as being related to a wide variety of known
cancers: cervical, oropharyngeal, anal, vaginal, penile, and skin. For some of these cancers …

Head and neck squamous cell cancers (HNSCCs) represent a diverse group of tumors
emerging within different mucosal surfaces of the oral cavity, nasopharynx, oropharynx …

Simple Summary To better prevent/combat recurrence and identify predictive/targetable
markers upon diagnosis, we performed whole-exome sequencing (WES) of primary tumours …

Although not completely understood, the role of the Hedgehog-GLI (HH-GLI) signaling
pathway in melanoma and epithelial skin tumors has been reported before. In this study, we …

The most common tumor affecting the head and neck is head and neck squamous cell
carcinoma (HNSCC). The characteristics of HNSCC include a rapid onset, a lack of early …

Background The immune profile in primary resected hypopharyngeal squamous cell
carcinoma (HPSCC) and its prognostic value remain to be defined. Methods We enrolled …

Background Human papillomaviruses have been shown to dysregulate the gene expression
and DNA methylation profiles of their host cells over the course of infection. However, there …

Objective: We aimed to analyze the significance of oral hygiene in patients with squamous
cell carcinoma of the lower gingiva. Methods: Oral hygiene was assessed using a …